Team:BYU Provo

From 2011.igem.org

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{{Template:BYU_Provo}}
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==About Us==
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[[File:Doctor E.png|left|The Doctor]][[File:X ray E.png|right|X-Ray]]
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This is a template page. READ THESE INSTRUCTIONS.
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You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
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You <strong>MUST</strong> have a team description page, a project abstract, a complete project description, a lab notebook, and a safety page.  PLEASE keep all of your pages within your teams namespace. 
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In keeping with BYU's tradition of excellence, our team will represent BYU and all it stands for at the iGEM competition in Indiana, then Boston this year.  This will be the first year that a team from BYU will be competing and we plan to demonstrate what Cougars are capable of.
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==Project Description==
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The International Genetically Engineered Machine competition (iGEM) is the world's premier synthetic biology competition. Last year 130+ teams from all continents participated. As BYU's first iGEM team, we propose constructing a molecular AND gate in E. coli. An AND gate requires two positive inputs to generate a positive output.  To detect our chosen inputs we are investigating the OxyR promoter and a thermo-sensitive riboswitch. The OxyR protein activates transcription in the presence of hydrogen peroxide, a reactive oxygen species (ROS). The riboswitch allows translation only above a specific temperature. Both inputs activate a Cre/Lox system to remove a terminator sequence and allow transcription of a molecular signal. We intend to express this system in E. coli where, in the presence of both inputs, the cells will produce green fluorescent protein. A similar system, in theory, could be used for early detection of colorectal cancer.
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==Project Video==
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|You can write a background of your team here.  Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
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<html><iframe width="560" height="345" src="http://www.youtube.com/embed/hkYrQJqXPEc" frameborder="0" allowfullscreen></iframe></html>
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|[[Image:BYU_Provo_logo.png|200px|right|frame]]
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''Tell us more about your project. Give us background.  Use this as the abstract of your project.  Be descriptive but concise (1-2 paragraphs)''
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|[[Image:BYU_Provo_team.png|right|frame|Your team picture]]
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|align="center"|[[Team:BYU_Provo | Team Example]]
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{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
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!align="center"|[[Team:BYU_Provo|Home]]
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To learn more about the iGEM competition, visit this link: [https://igem.org/Main_Page iGEM Website] [[File:IGemGray.png|150px]]
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!align="center"|[[Team:BYU_Provo/Team|Team]]
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!align="center"|[https://igem.org/Team.cgi?year=2011&team_name=BYU_Provo Official Team Profile]
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!align="center"|[[Team:BYU_Provo/Project|Project]]
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!align="center"|[[Team:BYU_Provo/Parts|Parts Submitted to the Registry]]
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!align="center"|[[Team:BYU_Provo/Modeling|Modeling]]
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!align="center"|[[Team:BYU_Provo/Notebook|Notebook]]
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!align="center"|[[Team:BYU_Provo/Safety|Safety]]
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!align="center"|[[Team:BYU_Provo/Attributions|Attributions]]
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Latest revision as of 18:23, 17 January 2012

Team BYU Provo

BYU Provo
 

About Us

The Doctor
X-Ray

In keeping with BYU's tradition of excellence, our team will represent BYU and all it stands for at the iGEM competition in Indiana, then Boston this year. This will be the first year that a team from BYU will be competing and we plan to demonstrate what Cougars are capable of.




Project Description

The International Genetically Engineered Machine competition (iGEM) is the world's premier synthetic biology competition. Last year 130+ teams from all continents participated. As BYU's first iGEM team, we propose constructing a molecular AND gate in E. coli. An AND gate requires two positive inputs to generate a positive output. To detect our chosen inputs we are investigating the OxyR promoter and a thermo-sensitive riboswitch. The OxyR protein activates transcription in the presence of hydrogen peroxide, a reactive oxygen species (ROS). The riboswitch allows translation only above a specific temperature. Both inputs activate a Cre/Lox system to remove a terminator sequence and allow transcription of a molecular signal. We intend to express this system in E. coli where, in the presence of both inputs, the cells will produce green fluorescent protein. A similar system, in theory, could be used for early detection of colorectal cancer.

Project Video


To learn more about the iGEM competition, visit this link: iGEM Website IGemGray.png