Team:TU-Delft/Project/Modelling
From 2011.igem.org
(Difference between revisions)
CarstenBlom (Talk | contribs) (→Modelling) |
CarstenBlom (Talk | contribs) (→Modelling) |
||
Line 24: | Line 24: | ||
The intracellular module gives us information about the adhesiveness of Mfp-5 on the membrane which is directly dependent on the inducer (L-arabinose) concentration. It includes all steps in between the inducer (induction of the Mfp-5 expression?) and the amount of Mfp-5 eventually present on the outer membrane, such as for example the influence of the transcription factor, the efficiency of DNA-polymerase and the ribosome concentration in relation to the specific growth rate μ. | The intracellular module gives us information about the adhesiveness of Mfp-5 on the membrane which is directly dependent on the inducer (L-arabinose) concentration. It includes all steps in between the inducer (induction of the Mfp-5 expression?) and the amount of Mfp-5 eventually present on the outer membrane, such as for example the influence of the transcription factor, the efficiency of DNA-polymerase and the ribosome concentration in relation to the specific growth rate μ. | ||
- | [[File:Mechanical_model_regulatory_level.jpg| | + | [[File:Mechanical_model_regulatory_level.jpg|400px]] |
The intercellular module gives us information about cell physiology dependent on cell adhesiveness and environmental parameters. With this part of our model, we try to predict cell clustering and its related settling time. This includes factors as buoyancy, cluster formation and degradation, growth and death.(etc. not necessary because you say “includes”). | The intercellular module gives us information about cell physiology dependent on cell adhesiveness and environmental parameters. With this part of our model, we try to predict cell clustering and its related settling time. This includes factors as buoyancy, cluster formation and degradation, growth and death.(etc. not necessary because you say “includes”). | ||
In the end, our intracellular module will lead to a useful output, namely the adhesive properties of Mfp-5 in relation to the inducer. This output is directly the input for the intercellular model. Combination of as well the intracellular as the intercellular models enables us to predict the behaviour of cells in a growth medium, which is directly dependent on the concentration of the inducer L-arabinose. | In the end, our intracellular module will lead to a useful output, namely the adhesive properties of Mfp-5 in relation to the inducer. This output is directly the input for the intercellular model. Combination of as well the intracellular as the intercellular models enables us to predict the behaviour of cells in a growth medium, which is directly dependent on the concentration of the inducer L-arabinose. | ||
- | [[File:Mechanical_model_intercellular_module.jpg| | + | [[File:Mechanical_model_intercellular_module.jpg|400px]] |
Revision as of 20:40, 21 September 2011