Team:Queens Canada/Project/Intro
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- | < | + | <h3green>Project Description</h3green> <p> |
<regulartext>The nematode worm C. elegans does not normally chemotax toward environmental pollutants like naphthalene, toluene, phenol, and DDT. However, certain G-protein coupled receptors found in H. sapiens, M. musculus, and R. norvegicus are agonized by these compounds. Our main goal is to import these foreign GPCRs into the worm in the hopes of observing novel chemotaxis behaviour. Secondarily, we will design a field bioassay based on our C. elegans chemotaxis system. We envision two populations of worms expressing different types of fluorescent protein. One population will be repulsed by toxic compounds, and one will chemotax toward those compounds. The presence of toxicity in a soil sample would be indicated by a ring of one type of fluorescence forming around the sample. <p> </regulartext> | <regulartext>The nematode worm C. elegans does not normally chemotax toward environmental pollutants like naphthalene, toluene, phenol, and DDT. However, certain G-protein coupled receptors found in H. sapiens, M. musculus, and R. norvegicus are agonized by these compounds. Our main goal is to import these foreign GPCRs into the worm in the hopes of observing novel chemotaxis behaviour. Secondarily, we will design a field bioassay based on our C. elegans chemotaxis system. We envision two populations of worms expressing different types of fluorescent protein. One population will be repulsed by toxic compounds, and one will chemotax toward those compounds. The presence of toxicity in a soil sample would be indicated by a ring of one type of fluorescence forming around the sample. <p> </regulartext> |
Revision as of 20:44, 20 June 2011