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Team:Cambridge
From 2011.igem.org
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Welcome to the Cambridge iGEM 2011 team's wiki! | Welcome to the Cambridge iGEM 2011 team's wiki! | ||
| - | If you would like to contact the Cambridge iGEM 2011 team, please | + | If you would like to contact the Cambridge iGEM 2011 team, please email us at [mailto:cambridgeigem2011@gmail.com cambridgeigem2011@gmail.com] or find us on [http://twitter.com/#!/Cam_iGEM_2011 Twitter]. |
==''Bact'''iridescence'''''== | ==''Bact'''iridescence'''''== | ||
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As part of our iGEM project we propose to express reflectin in-vivo within ''Escherichia coli'' to reproduce the same multi-layer structure. Further we wish to demonstrate the ability to [[Team:Cambridge/Project#diridescence|dynamically tune]] structural colour in-vivo through phosphorylation. Our work will directly impact upon the design of next-generation of novel biosensors. | As part of our iGEM project we propose to express reflectin in-vivo within ''Escherichia coli'' to reproduce the same multi-layer structure. Further we wish to demonstrate the ability to [[Team:Cambridge/Project#diridescence|dynamically tune]] structural colour in-vivo through phosphorylation. Our work will directly impact upon the design of next-generation of novel biosensors. | ||
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==Editing the wiki== | ==Editing the wiki== | ||
Revision as of 11:35, 2 August 2011
Welcome to the Cambridge iGEM 2011 team's wiki!
If you would like to contact the Cambridge iGEM 2011 team, please email us at cambridgeigem2011@gmail.com or find us on Twitter.
Bactiridescence
Reflectins are a recently identified protein family rich in aromatic and sulphur-containing amino acids, responsible for the 'reflective' camouflage exhibited by certain cephalopods. To date, researchers have isolated the protein, reproduced it using Escherichia coli and shown it to exhibit self-assembling behaviour which leads to dynamic manipulation of incident light.
Under in-vitro conditions Kramer et. al produced thin films, photonic gratings and fibres which exhibited structural colour extending across the entire visual spectrum by varying the thickness. In particular the colour change was demonstrated to be reversible. It is hypothesized the colouration is a result of thin film interference.
Within the Atlantic squid Loligo pealeii, Morse et.al found a multi-layer alternating structure of iridophore platelets of reflectin and an unidentified material, each possessing different refractive indices. By studying tissue samples in-vitro the researchers observed conformational changes in the multi-layer structure due to phosphorylation.
As part of our iGEM project we propose to express reflectin in-vivo within Escherichia coli to reproduce the same multi-layer structure. Further we wish to demonstrate the ability to dynamically tune structural colour in-vivo through phosphorylation. Our work will directly impact upon the design of next-generation of novel biosensors.
Editing the wiki
To make a new page with all the right formatting, navigate to the page you want to create, click edit (you have to be logged in) and paste the following into the edit box, then work away. (I find this helpful.)
{{Template:Team:Cambridge/CAM_2011_TEMPLATE_HEAD}}
==Page Title==
Your text here
{{Template:Team:Cambridge/CAM_2011_TEMPLATE_FOOT}}
