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Team:British Columbia/Model3
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<html><h3>Three-dimensional structure of the 3 terpene synthases</h3></html><p></p> | <html><h3>Three-dimensional structure of the 3 terpene synthases</h3></html><p></p> | ||
[[File:UBCiGEM superimposed synthases.jpg]] | [[File:UBCiGEM superimposed synthases.jpg]] | ||
| - | <p></p>Superimposition of the 3D structures of alpha-pinene synthase (blue), beta-pinene synthase (red), and limonene synthase (green). We used MODELLER (1) to automate homology-based 3D structure prediction. We identified an experimentally determined 3D structure of a taxadiene synthase from Pacific Yew (PDB ID: 3P5R) as an appropriate template.<p></p> | + | <p></p>Superimposition of the 3D structures of alpha-pinene synthase (blue), beta-pinene synthase (red), and limonene synthase (green). We used MODELLER (1) to automate homology-based 3D structure prediction. We identified an experimentally determined 3D structure of a taxadiene synthase from Pacific Yew (PDB ID: 3P5R) as an appropriate template. The image was taken using the freely available ICM Browser.<p></p> |
<b>Reactive site of the three synthases</b><p></p> | <b>Reactive site of the three synthases</b><p></p> | ||
Revision as of 02:41, 29 October 2011
Monoterpene Synthase Structural Modeling
Three-dimensional structure of the 3 terpene synthases
Magnesium ions are cofactors located at the reactive site.
Future Directions
References
1. N. Eswar, M. A. Marti-Renom, B. Webb, M. S. Madhusudhan, D. Eramian, M. Shen, U. Pieper, A. Sali. Comparative Protein Structure Modeling With MODELLER. Current Protocols in Bioinformatics, John Wiley & Sons, Inc., Supplement 15, 5.6.1-5.6.30, 2006.
