Team:Brown-Stanford/Biosensor/Overview

From 2011.igem.org

(Difference between revisions)
(Project Overview)
 
(2 intermediate revisions not shown)
Line 2: Line 2:
== '''Project Overview''' ==
== '''Project Overview''' ==
-
Problem: How will we know if our cultures are okay?
+
Biosensor is a novel mechanism of FRET reporting using engineered parts of the bacterial cellulosome in the form of cohesin-dockerin pairs. We will create a two cohesin complex to bring together constitutive RFP and CFP reporters bound to dockerins. The cohesin complex will cause FRET reporting that should be faster than traditional methods which require maturation of GFP-based reporters.
-
*We need to monitor genetic health of ''E. coli'' to ensure the survival and utility of the culture
+
-
Solution: DNA sensor that reports on DNA damage
+
-
[[File:Brown-Stanford CohesinDockerin.png|center|600px]]
+
[[File:Brown-Stanford CohesinDockerin.png|center|400px]]
{{:Team:Brown-Stanford/Templates/Foot}}
{{:Team:Brown-Stanford/Templates/Foot}}

Latest revision as of 21:25, 14 July 2011

Brown-Stanford
iGEM

Project Overview

Biosensor is a novel mechanism of FRET reporting using engineered parts of the bacterial cellulosome in the form of cohesin-dockerin pairs. We will create a two cohesin complex to bring together constitutive RFP and CFP reporters bound to dockerins. The cohesin complex will cause FRET reporting that should be faster than traditional methods which require maturation of GFP-based reporters.

Brown-Stanford CohesinDockerin.png