Signalling is nothing without control...

Mathematical modelling page

Mathematical modelling plays nowadays a central role in Synthetic Biology, due to its ability to serve as a crucial link between the concept and realization of a biological circuit. According to this, after a brief overview about the advantages that modelling engineered circuits can bring, we deeply analyze the system of equation formulas, underlining the role and the function of the parameters involved in the model. Then, experimental procedures for parameters estimation are presented and, finally, different types of circuit are presented and their simulations performed, using ODE's with MATLAB and explainig the difference between a closed-loop model and an open one.