Team:ETH Zurich/Modeling/Parameters
From 2011.igem.org
Parameter | Description | Value | Reference |
αTetR | TetR production rate | 3.93 μM/min | [5] |
αC | CI production rate | 1 μM/min | [1] |
αL1 | LacI production rate | 1 μM/min | [1] |
αL2 | LacIM1 production rate | 1 μM/min | [1] |
αG | GFP production rate | 2 μM/min | [1] |
αLuxI | LuxI production rate | 1 μM/min | [7] |
αLuxI | LuxI production rate | 1 μM/min | [7] |
αLuxI | LuxI production rate | 1 μM/min | [7] |
ks1 | AHLi production rate | 0.01 1/min | [2] |
ρR | LuxR-AHL dimerization rate | 0.5 1/μM3min | [1] |
αRFP | RFP production rate | 1 μM/min | a. |
βAcA | Acetaldehyde repression coefficient | 7.124 μM | [5] |
βT | TetR repression coefficient | 0.01 μM | a. |
βC | CI repression coefficient | 0.008 μM | [1] |
βL | LacI repression coefficient | 0.8 μM | [1] |
θR | LuxR-AHL activation coefficient | 0.01 μM | [1] |
γTetR | TetR degradation rate | 0.0692 1/min | a. |
γC | CI degradation rate | 0.0692 1/min | [1] |
γL | LacI degradation rate | 0.0231 1/min | [1] |
γG | GFP degradation rate | 0.0692 1/min | [1] |
γLuxI | LuxI degradation rate | 0.0167 1/min | [3] |
ks0 | AHLi degradation rate | 1 1/min | [2] |
kse | AHLe degradation rate | 1 1/min | [2] |
γR | LuxR-AHL degradation rate | 0.0231 1/min | [1] |
γRFP | RFP degradation rate | 0.0041 1/min | [4] |
n1 | LacI cooperativity coefficient | 2 | [1] |
n2 | CI cooperativity coefficient | 2 | [1] |
n3 | TetR cooperativity coefficient | 2 | [2] |
n4 | LuxR-AHL cooperativity coefficient | 1 | [1] |
n5 | AlcR-AcA cooperativity coefficient | 1.352 | [5] |
η | Diffusion rate across the cell membrane | 2 | [2] |
ηext | Average diffusion rate for all cells | 1 | [2] |
N | Number of cells | 1 | a. |
aXylR | XylR production rate | 95.5 uM/min | [7] |
n6 | Xylene cooperativity coefficient | 2 | [7] |
γXylR | XylR degradation rate | 0.03553 1/min | a. |
KXyl | Xylene activation coefficient | 40 uM | [7] |
KXylR | XylR activation coefficient | 1.419*10-3 uM | [6] |
n7 | XylR cooperativity coefficient | 5 | [6] |
a. - assumption