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Team:ETH Zurich
From 2011.igem.org
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| - | |style="font-size:2em; | + | |style="font-size:2em; heigh 30px" class="overview"|Overview of the system |
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|[[File:ETHZ-overview.png|700px|center|thumb|Overview of our system]] | |[[File:ETHZ-overview.png|700px|center|thumb|Overview of our system]] | ||
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|Link to Data Page goes here | |Link to Data Page goes here | ||
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| + | |style="font-size:2em; heigh 30px" class="overview"|Our Sponsors | ||
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| + | <html><a href="http://www.basf.ch" target="_blank"></html>[[File:ETHZ-BASF.png|250px|link=]]<html></a> </html> | ||
| + | <html><a href="http://www.lonza.com" target="_blank"></html>[[File:ETHZ-Lonza.png|250px|link=]]<html></a> </html> | ||
| + | <html><a href="http://www.merckserono.com" target="_blank"></html>[[File:ETHZ-Merck_Serono.png|250px|link=]]<html> </a> </html> | ||
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| + | <html><a href="http://www.novartis.ch" target="_blank"></html>[[File:ETHZ-Novartis.png|250px|link=]]<html></a> </html> | ||
| + | <html><a href="http://www.roche.ch" target="_blank"></html>[[File:ETHZ-Roche.png|250px|link=]]<html></a> </html> | ||
| + | <html><a href="http://www.syngenta.com" target="_blank"></html>[[File:ETHZ-Syngenta.png|250px|link=]]<html></a> </html> | ||
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Revision as of 20:36, 20 September 2011
| SmoColi |
| SmoColi is a bacterio-quantifier of acetaldehyde concentration that can be used as a passive smoke detector. Acetaldehyde is a toxic and carcinogenic component of cigarette smoke. It has a boiling point of 20.2 °C and is very volatile, thus can be used as an information carrier through air. The SmoColi cells are immobilized in an agarose-filled microfluidic device. The test solution is fed to one end of a microfluidic channel, in which an acetaldehyde gradient is established by diffusion and synthetic cellular degradation. The cells are engineered to sense acetaldehyde by a synthetically re-designed fungal acetaldehyde-responsive transactivator. The sensor is linked to a band-pass filter that drives GFP expression. This allows establishment of an input-concentration-dependent, moving fluorescent band displaying quantitative information about acetaldehyde. Finally, if the acetaldehyde concentration exceeds the threshold of malignance, a quorum-sensing-based mCherry alarm system springs into action, turning the entire device red. |
| Overview of the system |
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| Link to Data Page goes here |
| Our Sponsors |
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