Team:ETH Zurich

From 2011.igem.org

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|style="font-size:2em; height: 30px" class="overview" valign="top"|Smoke Sensors
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|align="center"|[[File:Design2.png|380px|center|link=Team:ETH_Zurich/Overview/CircuitDesign]] '''Sensor Design 1:''' Acetaldehyde Sensor
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{{:Team:ETH Zurich/Templates/SlideShow|Items=<html>
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<div><img src="/wiki/images/3/39/ETHZ_FRONT_Slide_0.png" /></div>
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[[File:Alternative_Xylene_system.png|380px|center|link=Team:ETH_Zurich/Overview/CircuitDesign]] '''Sensor Design 2:''' Xylene Sensor
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|style="font-size:2em; height: 30px" class="overview"|Abstract
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<div><img src="/wiki/images/d/d6/ETHZ_FRONT_Slide_2.png" usemap="#Slide2"/>
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|valign="top" style="height:100%"|'''We create a bacterio-quantifier of smoke. SmoColi cells are engineered to sense toxic substances found in cigarette smoke. They are immobilized in a microfluidic channel, in which a concentration gradient of the toxic substance is established. The sensor is linked to a band-pass filter that leads to input-concentration-dependent GFP expression. Continuous increase of the input concentration and its detection, therefore, establishes a moving fluorescent band in the channel. Finally, if the input concentration exceeds a certain threshold, cells produce RFP and the device turns red.'''
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|style="font-size:2em; text-align: center" class="overview"|[[Team:ETH_Zurich/Achievements/Data_page|Data Page]]
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|style="font-size:2em; text-align: center" class="overview"|[[Team:ETH_Zurich/Biology/Detector|Network Elements]]
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|style="font-size:2em; text-align: center" class="overview"|[[Team:ETH_Zurich/Process/Validation|Microfluidics Evaluation]]
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|style="font-size:2em; text-align: center" class="overview"|[[Team:ETH_Zurich/Modeling/Combined|Combined Model]]
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|style="font-size:2em; height: 30px" class="overview" valign="top"|Team
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|valign="top"|[[File:GroupETH_irena_brightened_sky_darkened_auto_corrected.jpg|246px|center|The SmoColi Team|link=Team:ETH_Zurich/Team]]
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|style="font-size:2em; height: 30px" class="overview" valign="top"|Signal Processing by SmoColi
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|valign="top" style="text-align: center"|[[File:ETHZ-Overview_Information_Processing.png|600px|center|Overview of our system|link=Team:ETH_Zurich/Overview/CircuitDesign]]
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'''Overview of the information processing steps in SmoColi'''
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|style="font-size:2em; height: 30px" class="overview"|Our Sponsors
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<html>
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<a href="http://www.basf.ch" target="_blank"></html>[[File:ETHZ-BASF.png|220px|link=]]<html>
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</a>&nbsp;&nbsp;
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<a href="http://www.ethz.ch" target="_blank"></html>[[File:ETH_Zurich_Logo.png|220px|link=]]<html>
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</a>&nbsp;&nbsp;
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<a href="http://www.lonza.com" target="_blank"></html>[[File:ETHZ-Lonza.png|220px|link=]]<html>
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</a>&nbsp;&nbsp;
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<a href="http://www.merckserono.com" target="_blank"></html>[[File:ETHZ-Merck_Serono.png|250px|link=]]<html></a>&nbsp;&nbsp;
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<a href="http://www.novartis.ch" target="_blank"></html>[[File:ETHZ-Novartis.png|220px|link=]]<html>
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</a>&nbsp;&nbsp;
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<a href="http://www.roche.ch" target="_blank"></html>[[File:ETHZ-Roche.png|220px|link=]]<html>
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</a>&nbsp;&nbsp;
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<a href="http://www.syngenta.com" target="_blank"></html>[[File:ETHZ-Syngenta.png|220px|link=]]<html>
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</a>&nbsp;&nbsp;
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<a href="http://www.dsm.com" target="_blank"></html>[[File:DSM MasterLogo.png|220px|link=]]<html>
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<html></a> </html>
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<div><img src="/wiki/images/e/ed/ETHZ_FRONT_Slide_7.png" usemap="#Slide7" />
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<area shape="rect" alt="" title="" coords="518,117,758,190" href="/Team:ETH_Zurich/Team/Human_practices#7.10.11 CBB Get together afternoon" />
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{{:Team:ETH Zurich/Templates/SectionStart}}
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= Abstract =
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'''We create a bacterio-quantifier of smoke. SmoColi cells are engineered to sense toxic substances found in cigarette smoke. They are immobilized in a microfluidic channel, in which a concentration gradient of the toxic substance is established. The sensor is linked to a band-pass filter that leads to input-concentration-dependent GFP expression. Continuous increase of the input concentration and its detection, therefore, establishes a moving fluorescent band in the channel. Finally, if the input concentration exceeds a certain threshold, cells produce RFP and the device turns red.'''
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{{:Team:ETH Zurich/Templates/SectionEnd}}
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{{:Team:ETH Zurich/Templates/HeaderNewEnd}}

Revision as of 23:18, 25 October 2011

Can you feel the smoke tonight?
 

Contents

Abstract

We create a bacterio-quantifier of smoke. SmoColi cells are engineered to sense toxic substances found in cigarette smoke. They are immobilized in a microfluidic channel, in which a concentration gradient of the toxic substance is established. The sensor is linked to a band-pass filter that leads to input-concentration-dependent GFP expression. Continuous increase of the input concentration and its detection, therefore, establishes a moving fluorescent band in the channel. Finally, if the input concentration exceeds a certain threshold, cells produce RFP and the device turns red.

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