Team:Bielefeld-Germany/Project/Background/Technology

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MALDI-TOF

Matrix-assisted Laser Desorption/Ionization – Time of flight (MALDI-TOF) is a procedure to analyze large biomolecules by their mass. Before measuring, the analyte is cocristalized on an metal plate within a solid matrix, 3,5-dimethoxy-4-hydroxycinnamic acid (sinapinic acid) and 2,5-dihydroxybenzoic acid (DHB) are most commonly used.