Team:Groningen

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Revision as of 23:57, 21 September 2011 by Muzgus (Talk | contribs)


Welcome to the iGEM 2011 Groningen team page

Count coli - a synthetic biological counter

Our project aims to design a genetic device able to count and memorize the occurrences of an input signal. We achieved this by utilization of auto-inducing loops, that act as memory units, and an engineered riboregulator, acting as an AND gate. The design of the device is modular, allowing free change of both input and output signals. Each increase of the counter results in a different output signal. The design allows implementation of any number of memory units, as the AND gate design enables to extend the system in a hassle-free way. In order to tweak bistable autoinducing loops we need a very fast and robust method for characterizing parts. For this we have created a genetic algorithm that will enable us to find parameters of the parts used in the design. It also allows the combination of data from multiple experiments across models with overlapping components.


Our engineered biological abacus counting occurrences of cold shocks.

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Our team is based at the University of Groningen in the The Netherlands