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Team:Washington/Magnetosomes/mamDescriptions
From 2011.igem.org
Description of mamAB operon gene functions
| Gene | AMB Number | Cluster Membership | Member of 28 genes list? (specific*/related**) | Function Summary (Vesicle chain formation, and/or biomineralization) | Gene Function |
|---|---|---|---|---|---|
| mamH | amb0961 | mamAB | Related | unknown | N/A |
| mamI | amb0962 | mamAB | Specific | Vesicle, Chain Formation | >Loss of mamI causes no membrane formation, gene product is localized onto chains |
| mamE | amb0963 | mamAB; mam Islet | Related | >Membrane-bound serine protease required for magnetite formation; might control the localization of other magnetosome proteins | |
| mamJ | amb0964 | mamAB; mam Islet | Specific | Chain Formation | >Proper magnetosome chain organization/assembly |
| mamK | amb0965 | mamAB; mam Islet | Related | Chain Formation | >Required for proper magnetosome chain organization; *bacterial actin-like cytoskeleton protein required for proper alignment of the magnetosomes in a chain, shown to localize the mamI |
| mamL | amb0966 | mamAB; mam Islet | Specific | Vesicle, biomineralization | >Crucial to mangneosome membrane creation, shown to be spread across the cell membrane and sometimes forms lines |
| mamM | amb0967 | mamAB | Related | >Biomineralization, involved in iron transport, magnetite nucleation, or establishement of the proper chemical enviornment for magnetite synthesis in the magnetosome | |
| mamN | amb0968 | mamAB | Related | >Biomineralization, involved in iron transport, magnetite nucleation, or establishement of the proper chemical enviornment for magnetite synthesis in the magnetosome | |
| mamO | amb0969 | mamAB | Related | >Biomineralization, involved in iron transport, magnetite nucleation, or establishement of the proper chemical enviornment for magnetite synthesis in the magnetosome | |
| mamP | amb0970 | mamAB | Related | Biomineralization | >Loss of mamP causes weak magnetic response, with large but fewer crystals |
| mamA | amb0971 | mamAB | Related | >Required for magnetosome activation; activation of vessicles | |
| mamQ | amb0972 | mamAB; mam Islet | Related | >ORF; formation/maintenance of magnetosome membranes | |
| mamR | amb0973 | mamAB | Specific | Chain formation, Biomineralization | >ORF; plays a role in controlling both particle number and size of magnetite cyrstals |
| mamB | amb0974 | mamAB | Related | Vesicle, Biomineralization | >Indirect role in magnetosome membrane invagination and biomineralization; magnetosome compartment formation |
| mamS | amb0975 | mamAB | Specific | unknown function | N/A |
| mamT | amb0976 | mamAB | Specific | Biomineralization | >Magnetite crystal growth; participates in different steps during magnetite synthesis |
| mamU | amb0977 | mamAB | Related | unknown function | N/A |
| mamV | amb0978 | mamAB | unknown function | N/A | N/A |
