Team:Paris Bettencourt/Modeling

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Team IGEM Paris 2011




Contents

Modeling

Direct observation

Characterization

Relevant parameters for modeling
Allosteric equations for modeling

T7 system

First T7 model without delay between receptor and amplifier
T7 model with delay between receptor and amplifier


tRNA amber system

The amber suppressor tRNA diffusion. The idea of the system is to pass tRNA amber molecules through the nanotubes. At every moment of time in the receiver cell there is a certain amount of transcripted mRNA-T7 among the others mRNA. The behavior of tRNA amber arrived to a receiver cell is random, so to describe its interaction with mRNA-T7 and its futher translation we can reason in terms of probability.

This system can be modelled after making some important assumptions :

  • All the molecules in the cell are uniformly distributed.
  • The number of tRNA amber diffused through the nanotubes is much more smaller than the one of the mRNA.



Master/Slave

Bi-directional communication









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