Team:Arizona State/Project/Software

We have developed a tool to assist in the development of synthetic CRISPR systems.

• Pick spacers from a source sequence, based on homology with the target genome, hairpinning potential, restriction sites, and known PAMs.
• Output arrays with various formats based on generated spacers.
• Display and gather CRISPR information using a database cultivated from several sources.

Downloads (coming soon)

• Python source:

• Dependencies: BioPython, NumPy, WxPython

• Executable:

Sources

• [http://crispr.u-psud.fr/crispr/ CrisprDB]
• [http://cmr.jcvi.org/tigr-scripts/CMR/CmrHomePage.cgi JCVI CMR]
• [http://crispi.genouest.org/ CRISPI]