Team:DTU-Denmark/Background overview

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Overview

Small RNA

DTU1 Central dogma with regulators.png

In our project we dig into the fascinating world of small RNA (sRNA) regulation with the aim of engeneering a so-called trap sRNA regulating module and hereby creating a universal tool for a whole new way of regulating gene expression in synthetic biology. To fully understand our project, at basic knowledge of sRNAs, the way they regulate gene expression, the players involved (the RNA chaperone Hfq) and the unique features of the regulation is required. So continue reading if these words are new to you.

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The chitobiose system

Chitobiose system.png

The project is inspired by the regulation of chitobiose uptake and metabolism in E. coli. Especially the following three players, which have been indentified independently in several organisms and thus goes by many names...

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