The idea

The chitobiose system in E. coli

The trap-RNA system can target any gene

The trap-RNA system provides unique flexibility for gene silencing in prokaryotes enabling control and tuning og gene expression. The specificity of the system depends on base pair complementarity. Therefore it can be designed to target any gene of interest by simply altering the sequences to match the target gene. Furthermore multiple trap-RNA systems can applied to the same biological circuit without interfering. Implementing sRNA and the trap-RNA into biological constructs they can be introduced by constitutive promoters or inducible promoters.