Team:UPO-Sevilla/Project/Improving Flip Flop/Modeling/Introduction
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Modeling
Introduction
In this chapter we model the modified toggle switch
To start, we include to this analysis the processes described at ‘Basic Bistable – Modeling’.
TRANSCRIPTION: RNAp + Promoter → RNAp + Promoter + mRNA
The mRNA production will be described using Michaelis-Menten kinetics:
TRANSLATION: mRNA + Ribosomes → mRNA + Ribosomes + Repressor
The Repressor production will be also modeled using Michaelis-Menten kinetics:
REPRESSION:
Promoter + n · Repressor → Promoter_Repressorn