Team:DTU-Denmark
From 2011.igem.org
What?
In this project a novel small RNA technology for gene silencing in bacteria is developed. The silencing is flexible and works in most bacteria. For more information go to [[Team:DTU-Denmark/Project|project overview]]. [[Team:DTU-Denmark/Methods_math#Dimensionless_analysis|derivation]]
Why?
Gene knockout is a fundamental technique in biology. It is currently a time-consuming process restricted to nonessential genes. For more perspectives go to [[Team:DTU-Denmark/Vision|project vision]].
How?
Inspired by the chitobiose system in E. coli we constructed a biological and mathematical model of the small RNA technology. For additional details go to [[Team:DTU-Denmark/Technical_stuff|technical stuff]].