Modeling

Predicting how our systems will react during experiments required precise modeling. Like in most synthetic biology projects, we created simulations of our gene regulation networks using Matlab. We also carefully thought about diffusion of very few molecule in a cell and proposed models of diffusion (wether it is passive, active or "assisted") in nanotubes to correcly model our systems. Those simulations were done using Matlab, Maya and a lot of reflexion.

	What is modeling in synthetic biology? You can finde here an introduction to our methods and the general idea behind most models in gene network.
	Our Hypotheses Because of the specificities of our project, we had to adapt the "classic" model to better represent our current situation. On top of that we made and justified a few other hypotheses detailed in this section.
	Modeling our designs Models predicting the behaviour of our designs are detailled in this section.
	Passive diffusion in nanotubes We investigate here the hypothesis of passive diffusion through nanotubes.
(Images are just here as an example, not definitive)	Assisted diffusion We propose here a model explaining how diffusion through nanotubes could be "assisted" by the tension differential between cell walls.

To the designs!

To the experiments!

Team:Paris Bettencourt/Modeling

From 2011.igem.org

Modeling