Team:ZJU-China
From 2011.igem.org
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<p><strong>X film</strong><br/> | <p><strong>X film</strong><br/> | ||
- | After we extend the behavior of rainbofilm, we think about some innovative ideas about biofilm.If we could rewire and even fine-tuning the input and output, this stratified expression system will act as a machine that recieve different inputs and make different responses just like <a href="http://en.wikipedia.org/wiki/Network_motif#Single-input_modules_.28SIM.29">single-input module</a>.Thus we would have a roubust and engineerable biofilm, called X film.<br/> | + | After we extend the behavior of rainbofilm, we think about some innovative ideas about biofilm.If we could rewire and even fine-tuning the input and output, this stratified expression system will act as a machine that recieve different inputs and make different responses just like <a href="http://en.wikipedia.org/wiki/Network_motif#Single-input_modules_.28SIM.29" target="_blank">single-input module</a>.Thus we would have a roubust and engineerable biofilm, called X film.<br/> |
Based on these ideas, we have come up with there subprojects:<br/> | Based on these ideas, we have come up with there subprojects:<br/> | ||
<strong>Sugarfilm:</strong>Using biofilm to produce fuel<br/><a href="https://2011.igem.org/Team:ZJU-China/X-Sugarfilm.html">>>go to Sugarfilm page</a><br/> | <strong>Sugarfilm:</strong>Using biofilm to produce fuel<br/><a href="https://2011.igem.org/Team:ZJU-China/X-Sugarfilm.html">>>go to Sugarfilm page</a><br/> |
Revision as of 19:50, 27 October 2011
Our Latest works
Rainbofilm Extension
we extend the current primitive stratification system into a more precise, more controllable, and more versatile device. We start with improving the input signals of the rainbofilm system by Fine-tuning the stratification pattern and Changing the differentiation signal.
>>go to rainbofilm extension page
X film
After we extend the behavior of rainbofilm, we think about some innovative ideas about biofilm.If we could rewire and even fine-tuning the input and output, this stratified expression system will act as a machine that recieve different inputs and make different responses just like single-input module.Thus we would have a roubust and engineerable biofilm, called X film.
Based on these ideas, we have come up with there subprojects:
Sugarfilm:Using biofilm to produce fuel
>>go to Sugarfilm page
Sensorfilm:Using biofilm as a more quantitative and robust biosensor with higher tolerance.
>>go to Sensorfilm page
Gluefilm:Using biofilm as two-sided tapes that becomes sticky only after two fitted surface are put together
>>go to Gluefilm page
Project
Rainbofilm is a stratified expression system in
biofilm, a self-organized module extensible for various needs.
Researchers found a vertical oxygen gradient establishes in the biofilm.
Such property allows us to use oxygen sensitive promoters to
artificially induce differentiated functions through the spatial
distribution of cells. Thus, the multi-step reaction can be processed
within the different layers of the biofilm.
The biofilm and its layered structure form spontaneously.
Also biofilm has the natural resistance to high levels of toxin. These
two properties render the Rainbofilm a convenient stable system for
bio-production and bio-sensor. The system can cater to different needs
simply by changing downstream genes. One possible application is ethanol
production. The cellulose is degraded to monose from the bottom to the
middle layer, and the ethanol is produced and secreted in the surface to
minimize the toxicity to the inner cells.
Team
We are a young and happy team of 13 scientists and engineers from very diverse backgrounds.Although this is our first year working on a wet lab project and biofilm experiments are new to us, we're currently taking great efforts to build the whole system for experiments.Our team progress and more info will be frequently updated so that our iGEM experience could be shared as much as possible along the way. We truly welcome you to contact us for any cooperation or suggestion.