Team:DTU-Denmark/Matlab
From 2011.igem.org
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[[File:DTU_Model8.txt]] | [[File:DTU_Model8.txt]] | ||
+ | |||
+ | <pre> | ||
+ | ********** MODEL NAME | ||
+ | Dimensionless form. Catalytical. | ||
+ | |||
+ | ********** MODEL NOTES | ||
+ | Kinetic model of trap-RNA system. | ||
+ | Parameters are estimated from literature. | ||
+ | |||
+ | ********** MODEL STATES | ||
+ | d/dt(m) = 1 - m - k_s*alpha_m*m*s/(beta_m*beta_s) | ||
+ | d/dt(s) = (beta_s/beta_m)*(alpha_s/alpha_m - s - k_r*alpha_m * s * r /(beta_s*beta_r)) | ||
+ | d/dt(r) = (beta_r/beta_m)*(alpha_r/alpha_m - r) | ||
+ | |||
+ | m(0) = 1 | ||
+ | s(0) = 0 | ||
+ | r(0) = 0 | ||
+ | |||
+ | ********** MODEL PARAMETERS | ||
+ | alpha_m = 10 | ||
+ | alpha_s = 0 | ||
+ | alpha_r = 0 | ||
+ | beta_m = 0.0257 | ||
+ | beta_s = 0.0257 | ||
+ | beta_r = 0.0257 | ||
+ | k_s = 0.00082 | ||
+ | k_r = 0.0082 | ||
+ | |||
+ | |||
+ | ********** MODEL VARIABLES | ||
+ | |||
+ | ********** MODEL REACTIONS | ||
+ | |||
+ | |||
+ | ********** MODEL FUNCTIONS | ||
+ | |||
+ | |||
+ | ********** MODEL EVENTS | ||
+ | event = gt(time,1), alpha_s, 40 | ||
+ | event = gt(time,3), alpha_r, 200 | ||
+ | event = gt(time,6), alpha_r, 0 | ||
+ | ********** MODEL MATLAB FUNCTIONS | ||
+ | </pre> | ||
The script running simulation and generating figures. | The script running simulation and generating figures. | ||
{{:Team:DTU-Denmark/Templates/Standard_page_end}} | {{:Team:DTU-Denmark/Templates/Standard_page_end}} |
Revision as of 02:25, 22 September 2011
Matlab code
Simulation
Temporal simulation is performed using the Systems Biology Toolbox 2 http://www.sbtoolbox.org/ environment with numerical integration using ode45. The used models.
********** MODEL NAME Dimensionless form. Catalytical. ********** MODEL NOTES Kinetic model of trap-RNA system. Parameters are estimated from literature. ********** MODEL STATES d/dt(m) = 1 - m - k_s*alpha_m*m*s/(beta_m*beta_s) d/dt(s) = (beta_s/beta_m)*(alpha_s/alpha_m - s - k_r*alpha_m * s * r /(beta_s*beta_r)) d/dt(r) = (beta_r/beta_m)*(alpha_r/alpha_m - r) m(0) = 1 s(0) = 0 r(0) = 0 ********** MODEL PARAMETERS alpha_m = 10 alpha_s = 0 alpha_r = 0 beta_m = 0.0257 beta_s = 0.0257 beta_r = 0.0257 k_s = 0.00082 k_r = 0.0082 ********** MODEL VARIABLES ********** MODEL REACTIONS ********** MODEL FUNCTIONS ********** MODEL EVENTS event = gt(time,1), alpha_s, 40 event = gt(time,3), alpha_r, 200 event = gt(time,6), alpha_r, 0 ********** MODEL MATLAB FUNCTIONS
The script running simulation and generating figures.