Team:Valencia

From 2011.igem.org

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==Water Colicin Cleaner: disinfected water by <i>E. coli</i>==
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<p>[[Image:Valencia logo.jpg|right|250px]]
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Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in <i>Escherichia coli</i>. As a proof of concept we have chosen to aim for enterobacteria, focusing on <i>E. coli</i> contaminated water, as a proxy of fecal water. The cleaning of <i>E. coli</i> will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.
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We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.
 
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W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.
 
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!align="center"|[[Team:Valencia|Home]]
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!align="center"|[[Team:Valencia/Team|Team]]
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!align="center"|[https://igem.org/Team.cgi?year=2011&team_name=Valencia Official Team Profile]
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!align="center"|[[Team:Valencia/Project|Project]]
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!align="center"|[[Team:Valencia/Modeling|Modeling]]
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!align="center"|[[Team:Valencia/Notebook|Notebook]]
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!align="center"|[[Team:Valencia/Safety|Safety]]
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<a class="bannertoplinks" href="https://2011.igem.org/Team:Valencia"><b>Home</b></a>
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</li>
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        <li>
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<a class="bannertoplinks" href="https://2011.igem.org/Team:Valencia/Team"><b>The team</b></a>
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                <ul style="z-index:1">
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Acknowledgements">Acknowledgements & Attributions</a></li>
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Gallery">Gallery</a></li>
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                                    </ul>
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</li>
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<a class="bannertoplinks" href="https://2011.igem.org/Team:Valencia/Project"><b>The project</b></a>
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                <ul style="z-index:1">
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Achievements">Achievements</a></li>
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Hardware">Hardware</a></li>
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Project1">Colicin production</a></li>
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Project2">pH-stat</a></li>
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Modeling">Modeling</a></li>
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Notebook/Calender">Notebook</a></li>
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<li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Protocols">Protocols</a></li>
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                </ul>
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<a class="bannertoplinks" href="https://2011.igem.org/Team:Valencia/Parts"><b>BioBricks</b></a>
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                <ul style="z-index:1">
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                </ul>
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        <li>
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<a class="bannertoplinks" href="https://2011.igem.org/Team:Valencia/Safety"><b>Human Practices</b></a>
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                <ul style="z-index:1">
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Safetyquestions">Biosafety and Biosecurity</a></li>
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<li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Safetycode">Deontological code</a></li>
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Experts">Asking the experts</a></li>
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                </ul>
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<div class=col_left_top>Water Colicin Cleaner: disinfected water by E. coli</div><!-- fin clase col_left_top-->
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<div class=col_left_center><p>Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in Escherichia coli. As a proof of concept we have chosen to aim for enterobacteria, focusing on E. coli contaminated water, as a proxy of fecal water. The cleaning of E. coli will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.</p>
 +
 
 +
<p>We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.</p>
 +
 
 +
<p>W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.</p> </div><!-- fin clase col_left_top-->
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<div class=col_left_bottom><img src="https://static.igem.org/mediawiki/2011/8/81/Valencia_logo.jpg"></div><!-- fin clase col_left_top-->
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</div><!-- fin clase col_left-->
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<div class=col_right_top>Who we are</div><!-- fin clase col_right_top-->
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Revision as of 14:06, 20 September 2011



Water Colicin Cleaner: disinfected water by E. coli

Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in Escherichia coli. As a proof of concept we have chosen to aim for enterobacteria, focusing on E. coli contaminated water, as a proxy of fecal water. The cleaning of E. coli will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.

We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.

W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.

Who we are

Retrieved from "http://2011.igem.org/Team:Valencia"