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Team:UPO-Sevilla/Project/Improving Flip Flop/Modeling/Introduction
From 2011.igem.org
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<h1>Modeling</h1> | <h1>Modeling</h1> | ||
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| + | <h2>Introduction</h2> | ||
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| + | <p>In this chapter we model the modified toggle switch</p> | ||
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| + | <p>To start, we include to this analysis the processes described at ‘Basic Bistable – Modeling’.</p> | ||
| + | |||
| + | <p><strong>TRANSCRIPTION:</strong> RNAp + Promoter → RNAp + Promoter + mRNA</p> | ||
| + | |||
| + | <p>The mRNA production will be described using Michaelis-Menten kinetics:</p> | ||
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| + | <p><strong>TRANSLATION:</strong> mRNA + Ribosomes → mRNA + Ribosomes + Repressor</p> | ||
| + | |||
| + | <p>The Repressor production will be also modeled using Michaelis-Menten kinetics:</p> | ||
| + | |||
| + | <p><strong>REPRESSION:</strong></p> Promoter + n · Repressor → Promoter_Repressor<sub>n</sub></p> | ||
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| + | <p></p> | ||
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| + | <p></p> | ||
| + | |||
| + | <p></p> | ||
| + | |||
| + | <p></p> | ||
Revision as of 00:00, 20 September 2011
Modeling
Introduction
In this chapter we model the modified toggle switch
To start, we include to this analysis the processes described at ‘Basic Bistable – Modeling’.
TRANSCRIPTION: RNAp + Promoter → RNAp + Promoter + mRNA
The mRNA production will be described using Michaelis-Menten kinetics:
TRANSLATION: mRNA + Ribosomes → mRNA + Ribosomes + Repressor
The Repressor production will be also modeled using Michaelis-Menten kinetics:
REPRESSION:
Promoter + n · Repressor → Promoter_Repressorn
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