Team:Valencia
From 2011.igem.org
(→Water Colicin Cleaner: disinfected water by E. coli) |
|||
Line 1: | Line 1: | ||
<!-- *** What falls between these lines is the Alert Box! You can remove it from your pages once you have read and understood the alert *** | <!-- *** What falls between these lines is the Alert Box! You can remove it from your pages once you have read and understood the alert *** | ||
- | |||
<html> | <html> | ||
<div id="box" style="width: 700px; margin-left: 137px; padding: 1px; border: 5px solid #000; background-color: #fe2b33;"> | <div id="box" style="width: 700px; margin-left: 137px; padding: 1px; border: 5px solid #000; background-color: #fe2b33;"> | ||
Line 14: | Line 13: | ||
</div> | </div> | ||
</html> | </html> | ||
- | |||
*** End of the alert box *** --> | *** End of the alert box *** --> | ||
{{Template:Valencia-0-3}} | {{Template:Valencia-0-3}} | ||
==Water Colicin Cleaner: disinfected water by <i>E. coli</i>== | ==Water Colicin Cleaner: disinfected water by <i>E. coli</i>== | ||
- | <p>[[Image:Valencia logo.jpg|right| | + | <p>[[Image:Valencia logo.jpg|right|250px]] |
+ | Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in <i>Escherichia coli</i>. As a proof of concept we have chosen to aim for enterobacteria, focusing on <i>E. coli</i> contaminated water, as a proxy of fecal water. The cleaning of <i>E. coli</i> will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media. | ||
+ | |||
We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality. | We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality. | ||
+ | |||
W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases. | W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases. | ||
</p> | </p> | ||
Line 26: | Line 27: | ||
<!--- The Mission, Experiments | <!--- The Mission, Experiments | ||
- | |||
{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center" | {| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center" | ||
!align="center"|[[Team:Valencia|Home]] | !align="center"|[[Team:Valencia|Home]] |
Revision as of 15:39, 13 September 2011
Water Colicin Cleaner: disinfected water by E. coli
Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in Escherichia coli. As a proof of concept we have chosen to aim for enterobacteria, focusing on E. coli contaminated water, as a proxy of fecal water. The cleaning of E. coli will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.
We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.
W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.