Team:Peking R

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In our project, we aim at establishing an extensible and versatile platform for the softcoding of genetic program in bacteria, composed of a toolbox and a methodology. The toolbox consists of interoperable and truly modular ligand-responsive riboswitches/ribozymes, while the methodology is automated design of synthetic ribosome binding sites (RBS) with customized translation rate. When combining them together, a quantitative correlation between the concentration of specific ligand and synthetic RBS strength can be established. To learn more, please click here.