Team:Valencia

From 2011.igem.org

(Difference between revisions)
(Water Colicin Cleaner: disinfected water by E. coli)
Line 1: Line 1:
<!-- *** What falls between these lines is the Alert Box!  You can remove it from your pages once you have read and understood the alert ***
<!-- *** What falls between these lines is the Alert Box!  You can remove it from your pages once you have read and understood the alert ***
-
 
<html>
<html>
<div id="box" style="width: 700px; margin-left: 137px; padding: 1px; border: 5px solid #000; background-color: #fe2b33;">
<div id="box" style="width: 700px; margin-left: 137px; padding: 1px; border: 5px solid #000; background-color: #fe2b33;">
Line 14: Line 13:
</div>
</div>
</html>
</html>
-
 
  *** End of the alert box *** -->
  *** End of the alert box *** -->
{{Template:Valencia-0-3}}
{{Template:Valencia-0-3}}
==Water Colicin Cleaner: disinfected water by <i>E. coli</i>==
==Water Colicin Cleaner: disinfected water by <i>E. coli</i>==
-
<p>[[Image:Valencia logo.jpg|right|150px]]Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in <i>Escherichia coli</i>. As a proof of concept we have chosen to aim for enterobacteria, focusing on <i>E. coli</i> contaminated water, as a proxy of fecal water. The cleaning of <i>E. coli</i> will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.
+
<p>[[Image:Valencia logo.jpg|right|250px]]
 +
Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in <i>Escherichia coli</i>. As a proof of concept we have chosen to aim for enterobacteria, focusing on <i>E. coli</i> contaminated water, as a proxy of fecal water. The cleaning of <i>E. coli</i> will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.
 +
 
We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.
We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.
 +
W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.
W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.
</p>
</p>
Line 26: Line 27:
<!--- The Mission, Experiments  
<!--- The Mission, Experiments  
-
 
{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
!align="center"|[[Team:Valencia|Home]]
!align="center"|[[Team:Valencia|Home]]

Revision as of 15:39, 13 September 2011



Water Colicin Cleaner: disinfected water by E. coli

Valencia logo.jpg

Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in Escherichia coli. As a proof of concept we have chosen to aim for enterobacteria, focusing on E. coli contaminated water, as a proxy of fecal water. The cleaning of E. coli will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.

We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.

W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.