Team:Edinburgh/Conclusions

From 2011.igem.org

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Things shall be concluded.
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In our abstract, we asked a number of questions that our feasibility study was intended to answer.
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'''Would the efficiency of cellulases be increased by having different types close together?'''
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: Very probably. Our [[Team:Edinburgh/Cellulases (C model) | C model]] and [[Team:Edinburgh/Cellulases (Kappa model) | Kappa model]] showed that synergy makes sense ''in silico''.
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'''Could this be done by displaying them on a cell outer membrane?'''
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: This seems a promising approach. <partinfo>BBa_K265008</partinfo> seems a promising carrier for placing enzymes at high copy number on the ''E. coli'' outer membrane.
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'''Could it be done by displaying them on a phage?'''
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: Further work is needed to answer this question. There are [[Team:Edinburgh/Efficiency | theoretical reasons]] to expect that this is a challenging problem.
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'''Does the BioSandwich DNA assembly method work properly?'''
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'''How would a biorefinery involving either system actually be constructed?'''
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'''Would such a biorefinery be economically viable?'''
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'''What are the social implications of creating such a biorefinery?'''
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'''What are people's thoughts and feelings regarding this project?'''
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'''Should we (meaning society) actually build such a biorefinery?'''
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Revision as of 10:42, 12 September 2011

In our abstract, we asked a number of questions that our feasibility study was intended to answer.

Would the efficiency of cellulases be increased by having different types close together?

Very probably. Our C model and Kappa model showed that synergy makes sense in silico.

Could this be done by displaying them on a cell outer membrane?

This seems a promising approach. <partinfo>BBa_K265008</partinfo> seems a promising carrier for placing enzymes at high copy number on the E. coli outer membrane.

Could it be done by displaying them on a phage?

Further work is needed to answer this question. There are theoretical reasons to expect that this is a challenging problem.

Does the BioSandwich DNA assembly method work properly?

How would a biorefinery involving either system actually be constructed?

Would such a biorefinery be economically viable?

What are the social implications of creating such a biorefinery?

What are people's thoughts and feelings regarding this project?

Should we (meaning society) actually build such a biorefinery?