Team:UCSF

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<h3orange>Welcome!</h3orange><p>
<h3orange>Welcome!</h3orange><p>
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<regulartext>This year, the UCSF iGEM team will research how to develop artificial biofilms via yeast cell surface display. Our team will be working with the non-pathogenic yeast strain S. Cerevisiae. Our goal is to be able to control the forming of biofilms by the yeast cells. Many species of yeast and bacteria readily form biofilms as a means of survival. These biofilms are composed of cells that aggregate to each other or to a surface. This year, the UCSF iGEM team has researched how to develop artificial biofilms via yeast cell surface display. We are synthetically engineering S. cerevisiae to form biofilm-like interactions that we can control by inducing display of adhesive proteins on the surface. The surface display system that we are using takes advantage of the natural yeast mating receptors, Aga1 and Aga2. We have chosen adhesive proteins from a variety of other organisms in order to create a range of interactions between the cells. The synthetic cell adhesion and interactions we are creating can serve as a model for biofilm formation and other types of cell-cell adhesion. </regulartext><p>
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<regulartext>Many microbial cells form biofilms as a means of survival. Biofilms are formed when a large number of microbial cells aggregate together. This year, the UCSF iGEM team has engineered artificial biofilms via yeast cell surface display. We synthetically engineered <i>S. cerevisiae</i> to form tunable biofilm-like structures by inducing the display of adhesive proteins on their surface. By combining the natural yeast mating receptors – Aga1 and Aga2 – with adhesive proteins from a variety of organisms, we created several adhesive interactions among yeast cells. Our synthetic cell adhesions can serve as a model for biofilm formation and primitive multicellular structures.</regulartext><p>
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<regulartext> Learn more about <span class="classgreent"><a href="2011.igem.org/Team:UCSF">biofilms</a><span>, check out our <span class="classgreent"><a href="2011.igem.org/Team:UCSF">project description </a><span>or see awesome <span class="classgreent"><a href="2011.igem.org/Team:UCSF">pictures </a><span>from this summer! </regulartext>
 
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<h3orange>Photo Gallery</h3orange><p>
<h3orange>Photo Gallery</h3orange><p>
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<p>Slideshow of pictures coming soon!</p>
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<h3orange>Header</h3orange><p>
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<h3orange>Media</h3orange><p>
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<regulartext> Visit our <regulartext><span><a href="https://2011.igem.org/Team:UCSF/Video">Extras</a><span> page for our 2011 Team Video and hear San Francisco Mayor Ed Lee talk about his visit to our lab!</regulartext><p></center>
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<h3green>Special Thanks to Our Sponsors! </h3green><p>
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<h3orange>Special Thanks to Our Sponsors! </h3orange><p>
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<regulartext> Click <span class="classgreent"><a href="link">here</a><span> to see our I'm not really sure what yet.<p> </regulartext>  
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<h3orange1> More</h3orange1> <p>
 

Latest revision as of 03:50, 29 September 2011

introduction
the team
our project
parts
requisites
attributions
extras

Hello There! Click here to see our Google Site!
Welcome!

Many microbial cells form biofilms as a means of survival. Biofilms are formed when a large number of microbial cells aggregate together. This year, the UCSF iGEM team has engineered artificial biofilms via yeast cell surface display. We synthetically engineered S. cerevisiae to form tunable biofilm-like structures by inducing the display of adhesive proteins on their surface. By combining the natural yeast mating receptors – Aga1 and Aga2 – with adhesive proteins from a variety of organisms, we created several adhesive interactions among yeast cells. Our synthetic cell adhesions can serve as a model for biofilm formation and primitive multicellular structures.

Photo Gallery

Media

Visit our Extras page for our 2011 Team Video and hear San Francisco Mayor Ed Lee talk about his visit to our lab!

Special Thanks to Our Sponsors!


Retrieved from "http://2011.igem.org/Team:UCSF"