Team:Valencia

From 2011.igem.org

(Difference between revisions)
(→Water Colicin Cleaner: disinfected water by E. coli)
 
(20 intermediate revisions not shown)
Line 1: Line 1:
-
<!-- *** What falls between these lines is the Alert Box!  You can remove it from your pages once you have read and understood the alert ***
+
[[File:Valencia Bannerv4.jpg|945px|link=https://2011.igem.org/Team:Valencia]]
-
 
+
{{Template:Valencia-0-3}}
<html>
<html>
-
<div id="box" style="width: 700px; margin-left: 137px; padding: 1px; border: 5px solid #000; background-color: #fe2b33;">
 
-
<div id="template" style="text-align: center; font-weight: bold; font-size: large; color: #f6f6f6; padding: 5px;">
 
-
This is a template page. READ THESE INSTRUCTIONS.
 
-
</div>
 
-
<div id="instructions" style="text-align: center; font-weight: normal; font-size: small; color: #f6f6f6; padding: 0px;">
 
-
You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
 
-
</div>
 
-
<div id="warning" style="text-align: center; font-weight: bold; font-size: small; color: #f6f6f6; padding: 5px;">
 
-
You <strong>MUST</strong> have a team description page, a project abstract, a complete project description, a lab notebook, and a safety page.  PLEASE keep all of your pages within your teams namespace. 
 
-
</div>
 
-
</div>
 
-
</html>
 
-
*** End of the alert box *** -->
+
<body>
-
{{Template:Valencia-0-3}}
+
-
==Water Colicin Cleaner: disinfected water by <i>E. coli</i>==
+
-
<p>[[Image:Valencia logo.jpg|right|150px]]Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in <i>Escherichia coli</i>. As a proof of concept we have chosen to aim for enterobacteria, focusing on <i>E. coli</i> contaminated water, as a proxy of fecal water. The cleaning of <i>E. coli</i> will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.
+
-
We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.
+
-
W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.
+
-
</p>
+
-
<!--[[Image:Valencia logo face.png|200px|right|frame]]-->
+
-
<!--[[Image:Valencia_team.png|right|frame|Your team picture]]-->
+
-
<!--- The Mission, Experiments
+
<style type="text/css">
-
{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
+
img {
-
!align="center"|[[Team:Valencia|Home]]
+
display: block;
-
!align="center"|[[Team:Valencia/Team|Team]]
+
margin: auto;
-
!align="center"|[https://igem.org/Team.cgi?year=2011&team_name=Valencia Official Team Profile]
+
}
-
!align="center"|[[Team:Valencia/Project|Project]]
+
 
-
!align="center"|[[Team:Valencia/Parts|Parts Submitted to the Registry]]
+
.center {
-
!align="center"|[[Team:Valencia/Modeling|Modeling]]
+
 
-
!align="center"|[[Team:Valencia/Notebook|Notebook]]
+
width:965px;
-
!align="center"|[[Team:Valencia/Safety|Safety]]
+
height:auto;
-
!align="center"|[[Team:Valencia/Attributions|Attributions]]
+
margin-left:7px;
-
|}
+
        margin-right:32.5px;
-
--->
+
        margin-top:20px;
 +
margin-bottom:30px;
 +
}
 +
 
 +
.col_left{
 +
width:650px;
 +
        height:auto;
 +
float:left;
 +
background-color:transparent;
 +
 +
}
 +
 
 +
.col_left_top{
 +
width:610px;
 +
background-color:#0087ba;
 +
height:20px;
 +
font-family:Verdana, Arial, Helvetica, sans-serif;
 +
font-size:20px;
 +
color:#fff;
 +
padding:20px;
 +
}
 +
 
 +
.col_left_center{
 +
width:610px;
 +
        text-align:justify;
 +
        height: auto;
 +
font-family:Verdana, Arial, Helvetica, sans-serif;
 +
font-size:14px;
 +
color:black;
 +
padding:20px;
 +
}
 +
 
 +
.col_left_bottom{
 +
width:525px;
 +
        text-align:center;
 +
        height: auto;
 +
font-family:Verdana, Arial, Helvetica, sans-serif;
 +
font-size:14px;
 +
color:#fff;
 +
padding:20px;
 +
}
 +
 
 +
.col_right{
 +
width:290px;
 +
        margin-left:10px;
 +
float:left;
 +
background-color:transparent;
 +
height:auto;
 +
}
 +
 
 +
.col_right_top{
 +
width:250px;
 +
        background-color:#0087ba;
 +
height:20px;
 +
font-family:Verdana, Arial, Helvetica, sans-serif;
 +
font-size:20px;
 +
color:#fff;
 +
padding:20px;
 +
}
 +
 
 +
.col_right_center{
 +
width:200px;
 +
        height: auto;
 +
font-family:Verdana, Arial, Helvetica, sans-serif;
 +
font-size:14px;
 +
color:#666;
 +
padding:20px;
 +
}
 +
 
 +
.col_right_bottom{
 +
width:335px;
 +
        text-align:center;
 +
        height: auto;
 +
font-family:Verdana, Arial, Helvetica, sans-serif;
 +
font-size:14px;
 +
color:#fff;
 +
padding:20px;
 +
}
 +
 
 +
 
 +
 
 +
 
 +
 
 +
html, body {
 +
margin: 0;
 +
padding: 0;
 +
}
 +
 
 +
body {
 +
background:darkblue url(https://static.igem.org/mediawiki/2011/6/65/Valencia_Aguamitadinferior1500x800.jpg) repeat-x top fixed;
 +
 
 +
}
 +
 
 +
#globalWrapper { background-color: transparent; border: none; margin: 0; padding: 0;}
 +
#content{
 +
                background:transparent url("https://static.igem.org/mediawiki/2011/f/fd/Valencia_Transpa30a.png") center fixed repeat-y;
 +
                padding: 0px;
 +
        margin:0 auto;
 +
                border: none; 
 +
           
 +
 +
            }
 +
 
 +
</style>
 +
<script type="text/javascript"
 +
src="http://ajax.googleapis.com/ajax/libs/jquery/1.3/jquery.min.js"></script>
 +
<script type="text/javascript">
 +
$(document).ready(function() {
 +
$("ul#topnav li").hover(function() {
 +
$(this).css({ 'background' : 'transparent url(https://static.igem.org/mediawiki/2010/0/03/Valencia_navbar_active.gif) repeat-x'});
 +
$(this).find("span").show();
 +
} , function() { //on hover out...
 +
$(this).css({ 'background' : 'none'});
 +
$(this).find("span").hide();
 +
});
 +
 +
});
 +
</script>
 +
 
 +
<style type="text/css">
 +
 
 +
#headerlinks{
 +
      margin-left: -12px;
 +
}
 +
 
 +
#nav, #nav ul {
 +
padding: 0;
 +
list-style: none;
 +
}
 +
 
 +
.abstractext{
 +
float:right;
 +
width="400px"
 +
}
 +
 
 +
#nav a {
 +
display: block;
 +
        width: 149px;
 +
        height: 40px;
 +
        font-family:Verdana, Arial, Helvetica, sans-serif;
 +
}
 +
 
 +
#nav li {
 +
float: left;
 +
width: 149px;
 +
margin-right: 41px;
 +
}
 +
 
 +
#nav li ul {
 +
position: absolute;
 +
width: 130px;
 +
left: -999em;
 +
 +
}
 +
 
 +
#nav li:hover ul {
 +
left: auto;
 +
      text-decoration: none;
 +
      color: white !important;
 +
 
 +
}
 +
 
 +
#nav li:hover ul, #nav li.sfhover ul {
 +
left: auto;
 +
      text-decoration: none;
 +
      color: white !important;
 +
}
 +
 
 +
sfHover = function() {
 +
var sfEls = document.getElementById("nav").getElementsByTagName("LI");
 +
for (var i=0; i<sfEls.length; i++) {
 +
sfEls[i].onmouseover=function() {
 +
this.className+=" sfhover";
 +
}
 +
sfEls[i].onmouseout=function() {
 +
this.className=this.className.replace(new RegExp(" sfhover\\b"), "");
 +
}
 +
}
 +
}
 +
if (window.attachEvent) window.attachEvent("onload", sfHover);
 +
 +
 
 +
 
 +
body {
 +
font: 10px normal Verdana, Arial, Helvetica, sans-serif;
 +
 
 +
padding: 0;
 +
}
 +
h1 {
 +
font: 3em normal Verdana, 'Times New Roman', Times, serif;
 +
color: #333;
 +
margin: 0;
 +
padding: 5px 0;
 +
}
 +
h3 {
 +
font: 17px normal Verdana, 'Times New Roman', Times, serif;
 +
color: #0000;
 +
margin: 0;
 +
padding: 5px 0;
 +
margin: 10px;
 +
        text-align:justify;
 +
        margin-top: 8px;
 +
        margin-bottom: 20px;   
 +
        margin-left: 20px;
 +
        margin-right: 20px;
 +
}
 +
h1 small{
 +
font: 0.2em normal Verdana, Arial, Helvetica, sans-serif;
 +
text-transform:uppercase;
 +
letter-spacing: 1.5em;
 +
display: block;
 +
color: #fff;
 +
}
 +
.container {width: 970px; margin: 0 auto;}
 +
 
 +
.curved {
 +
        -moz-border-radius: 10px;
 +
        -webkit-border-radius: 10px;
 +
        behavior:url(border-radius.htc);
 +
}
 +
   
 +
 
 +
 
 +
 
 +
 
 +
ul#topnav {
 +
margin: 0; padding: 0;
 +
float: left;
 +
width: 970px;
 +
list-style: none;
 +
position: relative;
 +
font-size: 18.8px;
 +
background: url(topnav_stretch.gif) repeat-x;
 +
}
 +
ul#topnav li {
 +
float: left;
 +
margin: 0; padding: 0;
 +
border-right: 1px solid #555;
 +
}
 +
ul#topnav li a {
 +
padding: 10px 15px;
 +
display: block;
 +
color: darkblue;
 +
text-decoration: none;
 +
}
 +
li span {
 +
float: left;
 +
padding: 15px 0;
 +
position: absolute;
 +
left: 0; top:40px;
 +
display: none;
 +
width: 965px;
 +
background: lightblue;
 +
color: white;
 +
-moz-border-radius-bottomright: 5px;
 +
-khtml-border-radius-bottomright: 5px;
 +
-webkit-border-bottom-right-radius: 5px;
 +
-moz-border-radius-bottomleft: 5px;
 +
-khtml-border-radius-bottomleft: 5px;
 +
-webkit-border-bottom-left-radius: 5px;
 +
}
 +
ul#topnav li:hover span { display: block; }
 +
ul#topnav li span a { display: inline; }
 +
ul#topnav li span a:hover {text-decoration: underline;}
 +
</style>
 +
<script type="text/javascript"
 +
src="http://ajax.googleapis.com/ajax/libs/jquery/1.3/jquery.min.js"></script>
 +
<script type="text/javascript">
 +
$(document).ready(function() {
 +
 +
$("ul#topnav li").hover(function() { //Hover over event on list item
 +
$(this).css({ 'background' : '#1376c9 url(topnav_active.gif) repeat-x'}); //Add background color + image on hovered list item
 +
$(this).find("span").show(); //Show the subnav
 +
} , function() { //on hover out...
 +
$(this).css({ 'background' : 'none'}); //Ditch the background
 +
$(this).find("span").hide(); //Hide the subnav
 +
});
 +
 +
});
 +
</script>
 +
 
 +
 
 +
 
 +
 
 +
 
 +
<div class=center>
 +
 
 +
<div class=col_left>
 +
<div class=col_left_top>Water Colicin Cleaner: disinfected water by E. coli</div><!-- fin clase col_left_top-->
 +
<div class=col_left_center>
 +
<p>Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in Escherichia coli. As a proof of concept we have chosen to aim for enterobacteria, focusing on E. coli contaminated water, as a proxy of fecal water. The cleaning of E. coli will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.</p>
 +
 
 +
<p>We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.</p>
 +
 
 +
<p>W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.</p> </div><!-- fin clase col_left_top-->
 +
<div class=col_left_bottom><img src="https://static.igem.org/mediawiki/2011/4/4a/Valencia_Logologologo.gif"></div><!-- fin clase col_left_top-->
 +
</div><!-- fin clase col_left-->
 +
 
 +
<div class=col_right>
 +
<div class=col_right_top>Who we are</div><!-- fin clase col_right_top-->
 +
 
 +
<div class=col_right_center>
 +
<img src="https://static.igem.org/mediawiki/2011/b/b1/Valencia_Upvtranspa.gif"/ width="150"/>
 +
</div><!-- fin clase col_right_center-->
 +
 
 +
<div class=col_right_center>
 +
<img src="https://static.igem.org/mediawiki/2011/2/25/Valencia_Ucvtranspa.gif" width="200" />
 +
</div><!-- fin clase col_right_center-->
 +
 
 +
<div class=col_right_center>
 +
<img src="https://static.igem.org/mediawiki/2011/7/7a/Valencia_Uvtrasnpa.gif" width="150" />
 +
</div><!-- fin clase col_right_center-->
 +
 
 +
<div class=col_right_bottom></div><!-- fin clase col_right_bottom-->
 +
</div><!-- fin clase col_right-->
 +
 
 +
</div><!-- fin clase center-->
 +
 
 +
 
 +
 
 +
 
 +
 
 +
 
 +
 
 +
 
 +
 
 +
</body>
 +
 
 +
</html>

Latest revision as of 03:03, 22 September 2011

Valencia Bannerv4.jpg



Water Colicin Cleaner: disinfected water by E. coli

Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in Escherichia coli. As a proof of concept we have chosen to aim for enterobacteria, focusing on E. coli contaminated water, as a proxy of fecal water. The cleaning of E. coli will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.

We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.

W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.

Who we are

Retrieved from "http://2011.igem.org/Team:Valencia"