Team:Valencia/Prueba

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<ul id="topnav">
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    <li><a href="https://2011.igem.org/Team:Valencia">Home</a>
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        <span>
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<li>
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            <a href="https://2010.igem.org/Team:Valencia">Team</a> |
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<a class="bannertoplinks" href="https://2011.igem.org/Team:Valencia"><b>Home</b></a>
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            <a href="https://2010.igem.org/Team:Valencia#The Valencia IGEM Team 2010">The Valencia Team</a> |
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</li>
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            <a href="https://2010.igem.org/Team:Valencia#News">News</a>
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    <li>
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        <a href="https://2011.igem.org/Team:Valencia/Team">The Team</a>
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        <span>
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            <a href="https://2010.igem.org/Team:Valencia/Team">The Team</a> |
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            <a href="https://2010.igem.org/Team:Valencia/Universities">The Universities</a> |
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            <a href="https://2010.igem.org/Team:Valencia/Akw">Acknowledgements</a> |
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            <a href="https://2010.igem.org/Team:Valencia/Attributions">Attributions</a> |
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            <a href="https://2010.igem.org/Team:Valencia/Gallery">Gallery</a>
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    </li>
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    <li><a href="https://2011.igem.org/Team:Valencia/Project">The Project</a>
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        <span>
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            <a href="https://2010.igem.org/Team:Valencia/Project">Overview</a> |
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            <a href="https://2010.igem.org/Team:Valencia/Terraforming">Project 1</a> |
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            <a href="https://2010.igem.org/Team:Valencia/Technologies">Project 2</a> |
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            <a href="https://2010.igem.org/Team:Valencia/lea">Project 3</a> |
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            <a href="https://2010.igem.org/Team:Valencia/prion">Project 4</a>
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    </li>
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    <li>
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        <a href="https://2011.igem.org/Team:Valencia/Parts">The Parts</a>
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        <!--Subnav Starts Here-->
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        <span>
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            <a href="https://2010.igem.org/Team:Valencia/Parts">Submitted Biobricks</a> |
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            <a href="https://2010.igem.org/Team:Valencia/Parts#Making our Biobricks">Making our Biobricks</a> |
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            <a href="https://2010.igem.org/Team:Valencia/Notebook/Calender">Notebook</a>
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    </li>
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         <li>
         <li>
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         <a href="https://2011.igem.org/Team:Valencia/Modeling">Modeling</a>
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<a class="bannertoplinks" href="https://2011.igem.org/Team:Valencia/Team"><b>The team</b></a>
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                <ul style="z-index:1">
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Acknowledgements">Acknowledgements & Attributions</a></li>
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Gallery">Gallery</a></li>
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                                    </ul>
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</li>
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         <li>
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<a class="bannertoplinks" href="https://2011.igem.org/Team:Valencia/Project"><b>The project</b></a>
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                <ul style="z-index:1">
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Achievements">Achievements</a></li>
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Hardware">Hardware</a></li>
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Project1">Colicin production</a></li>
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Project2">pH-stat</a></li>
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Modeling">Modeling</a></li>
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Notebook/Calender">Notebook</a></li>
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<li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Protocols">Protocols</a></li>
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                </ul>
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</li>
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        <li>
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<a class="bannertoplinks" href="https://2011.igem.org/Team:Valencia/Parts"><b>BioBricks</b></a>
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                <ul style="z-index:1">
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</li>
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<a class="bannertoplinks" href="https://2011.igem.org/Team:Valencia/Safety"><b>Human Practices</b></a>
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                <ul style="z-index:1">
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Safetyquestions">Biosafety and Biosecurity</a></li>
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<li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Safetycode">Deontological code</a></li>
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                        <li><a class="bannerlinks" href="https://2011.igem.org/Team:Valencia/Experts">Asking the experts</a></li>
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                </ul>
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</ul>
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<br />
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<div class=center>
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<div class=col_left>
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<div class=col_left_top>Water Colicin Cleaner: disinfected water by E. coli</div><!-- fin clase col_left_top-->
 +
<div class=col_left_center>Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in Escherichia coli. As a proof of concept we have chosen to aim for enterobacteria, focusing on E. coli contaminated water, as a proxy of fecal water. The cleaning of E. coli will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.
 +
 
 +
We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.
 +
 
 +
W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases. </div><!-- fin clase col_left_top-->
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<div class=col_left_bottom><img src="https://static.igem.org/mediawiki/2011/8/81/Valencia_logo.jpg"></div><!-- fin clase col_left_top-->
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</div><!-- fin clase col_left-->
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<div class=col_right>
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<div class=col_right_top>Who we are</div><!-- fin clase col_right_top-->
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<div class=col_right_center>
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<img src="https://static.igem.org/mediawiki/2008/b/b7/Upv_logo.jpg"/ width="200"/>
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</div><!-- fin clase col_right_center-->
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<div class=col_right_center>
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<img src="https://static.igem.org/mediawiki/igem.org/c/c4/Valencia_UCVlogo2.jpg" width="200" />
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</div><!-- fin clase col_right_center-->
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<div class=col_right_center>
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<img src="https://static.igem.org/mediawiki/2008/2/2d/Uv_logo.gif" width="200" />
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</div><!-- fin clase col_right_center-->
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<div class=col_right_bottom></div><!-- fin clase col_right_bottom-->
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</div><!-- fin clase col_right-->
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</div><!-- fin clase center-->
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        <!--Subnav Starts Here-->
 
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        <span>
 
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            <a href="https://2010.igem.org/Team:Valencia/Modeling">Modeling 1</a>|
 
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        </span>
 
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        <!--Subnav Ends Here-->
 
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    </li>
 
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    <li>
 
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        <a href="#">Human Practices</a>
 
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        <!--Subnav Starts Here-->
 
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        <span>
 
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            <a href="https://2010.igem.org/Team:Valencia/Ethics">Ethics in terraforming</a> |
 
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            <a href="https://2010.igem.org/Team:Valencia/Safety">Safety</a>
 
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        </span>
 
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        <!--Subnav Ends Here-->
 
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    </li>
 
-
    <li><a href="https://2010.igem.org/Team:Valencia/Achievements">Achievements</a></li>
 
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    <li><a href="https://2010.igem.org/Team:Valencia/Contact">Contact</a></li>
 
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</ul>
 

Latest revision as of 10:38, 20 September 2011



Water Colicin Cleaner: disinfected water by E. coli
Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in Escherichia coli. As a proof of concept we have chosen to aim for enterobacteria, focusing on E. coli contaminated water, as a proxy of fecal water. The cleaning of E. coli will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media. We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality. W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.
Who we are