Team:Washington

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=<center>'''Make It or Break It: <br/> Diesel Production and Gluten Destruction, the Synthetic Biology Way'''</center>=
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<!-- *** What falls between these lines is the Alert Box!  You can remove it from your pages once you have read and understood the alert *** -->
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<center>Synthetic biology holds great promise regarding the production of important compounds, and the degradation of harmful ones. This summer, we harnessed the power of synthetic biology to meet the world’s needs for fuel and medicine.</center>
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[[Image:Washington_Fire.jpg|left|320px|borderless|link=https://2011.igem.org/Team:Washington/Alkanes/Background]]
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[[Image:Washington_Bottle.jpg|right|200px|borderless|link=https://2011.igem.org/Team:Washington/Celiacs/Background]]
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[https://2011.igem.org/Team:Washington/Alkanes/Background '''Make It: Diesel Production''']  We constructed a strain of ''Escherichia coli'' that produces a variety of alkanes, the main constituents of diesel fuel, by introducing a pair of genes recently shown to convert fatty acid synthesis intermediates into alkanes.   
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<div id="template" style="text-align: center; font-weight: bold; font-size: large; color: #f6f6f6; padding: 5px;">
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This is a template page. READ THESE INSTRUCTIONS.
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<div id="instructions" style="text-align: center; font-weight: normal; font-size: small; color: #f6f6f6; padding: 5px;">
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You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
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You <strong>MUST</strong> have a team description page, a project abstract, a complete project description, a lab notebook, and a safety page.  PLEASE keep all of your pages within your teams namespace.   
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[https://2011.igem.org/Team:Washington/Celiacs/Background '''Break It: Gluten Destruction''']  We identified a protease with gluten-degradation potential, and then reengineered it to have greatly increased gluten-degrading activity, allowing for the breakdown of gluten in the digestive track when taken in pill form. 
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[https://2011.igem.org/Team:Washington/Magnetosomes/Background '''iGEM Toolkits''']  To enable next-generation cloning of standard biological parts, we built BioBrick vectors optimized for Gibson assembly and used them to create the Magnetosome Toolkit: a set of 18 genes from an essential operon in magnetotactic bacteria which we are characterizing to create magnetic ''E. coli''.
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{|align="justify"
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[[File:Washington_Spacer.jpg|1px]]
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|You can write a background of your team here. Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
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[[Image:UW Diesel Front Page.png|300px|link=https://2011.igem.org/Team:Washington/Alkanes/Background]]
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|[[Image:Washington_logo.png|200px|right|frame]]
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[[File:Washington_Spacer.jpg|20px]]
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[[Image:UW Toolkits Front Page.png|300px|link=https://2011.igem.org/Team:Washington/Magnetosomes/Background]]
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[[File:Washington_Spacer.jpg|20px]]
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''Tell us more about your project. Give us background.  Use this as the abstract of your project.  Be descriptive but concise (1-2 paragraphs)''
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[[Image:UW Gluten Front Page.png|300px|link=https://2011.igem.org/Team:Washington/Celiacs/Background]]
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|[[Image:Washington_team.png|right|frame|Your team picture]]
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|align="center"|[[Team:Washington | Team Example]]
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<!--- The Mission, Experiments --->
 
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{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
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!align="center"|[[Team:Washington|Home]]
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[[File:Washington_Spacer.jpg|25px]]
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!align="center"|[[Team:Washington/Team|Team]]
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[[File:Washington_OSLI.png|frameless|border|150px|link=http://www.osli.ca|Oil Sands Leadership Intiative]]
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!align="center"|[https://igem.org/Team.cgi?year=2011&team_name=Washington Official Team Profile]
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[[File:Washington_Spacer.jpg|25px]]
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!align="center"|[[Team:Washington/Project|Project]]
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[[File:Washington_UniversitySeal.gif|frameless|border|100px|link=http://www.washington.edu|University of Washington]]
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!align="center"|[[Team:Washington/Parts|Parts Submitted to the Registry]]
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[[File:Washington_Spacer.jpg|25px]]
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!align="center"|[[Team:Washington/Modeling|Modeling]]
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[[File:Washington_ARPA-E_Logo.png|frameless|border|150px|link=http://arpa-e.energy.gov/ProgramsProjects/Electrofuels.aspx|Advanced Research Projects Agency - Energy]]
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!align="center"|[[Team:Washington/Notebook|Notebook]]
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[[File:Washington_Spacer.jpg|25px]]
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!align="center"|[[Team:Washington/Safety|Safety]]
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[[File:Washington2011_Hhmi_362_72.jpg|link=http://www.hhmi.org/|Howard Hughes Medical Institute]]
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!align="center"|[[Team:Washington/Attributions|Attributions]]
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[[File:Washington_Spacer.jpg|25px]]
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[[File:Washington2011_NSFlogo.jpg|frameless|border|link=http://www.nsf.gov/|National Science Foundation]]
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[[File:Washington_Spacer.jpg|25px]]
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[[File:Washington_Anaspec.gif|frameless|border|100px|link=http://www.anaspec.com|Anaspec]]

Latest revision as of 17:01, 2 December 2011


Make It or Break It:
Diesel Production and Gluten Destruction, the Synthetic Biology Way

Synthetic biology holds great promise regarding the production of important compounds, and the degradation of harmful ones. This summer, we harnessed the power of synthetic biology to meet the world’s needs for fuel and medicine.


borderless
borderless

Make It: Diesel Production We constructed a strain of Escherichia coli that produces a variety of alkanes, the main constituents of diesel fuel, by introducing a pair of genes recently shown to convert fatty acid synthesis intermediates into alkanes.

Break It: Gluten Destruction We identified a protease with gluten-degradation potential, and then reengineered it to have greatly increased gluten-degrading activity, allowing for the breakdown of gluten in the digestive track when taken in pill form.

iGEM Toolkits To enable next-generation cloning of standard biological parts, we built BioBrick vectors optimized for Gibson assembly and used them to create the Magnetosome Toolkit: a set of 18 genes from an essential operon in magnetotactic bacteria which we are characterizing to create magnetic E. coli.


Washington Spacer.jpg UW Diesel Front Page.png Washington Spacer.jpg UW Toolkits Front Page.png Washington Spacer.jpg UW Gluten Front Page.png Washington Spacer.jpg



Washington Spacer.jpg Oil Sands Leadership Intiative Washington Spacer.jpg University of Washington Washington Spacer.jpg Advanced Research Projects Agency - Energy Washington Spacer.jpg Howard Hughes Medical Institute Washington Spacer.jpg National Science Foundation Washington Spacer.jpg Anaspec

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