Team:Groningen

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You are provided with this team page template with which to start the iGEM season. You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
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=<center>Welcome to the iGEM 2011 Groningen team page</center>=
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==Count coli - a synthetic biological counter==
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<html><center><div style="width: 500px; text-align: justify">Our project aims to design a genetic device able to count and memorize the occurrences of an input signal. We achieved this by utilizing auto-inducing loops that act as memory units, and an engineered riboregulator acting as an AND gate. This design of the device is modular allowing free change of both input and output signals. Each increase of the counter results in a different output signal. The design allows implementation of any number of memory units, as the AND gate design enables us to extend the system in a hassle-free way. In order to tweak bistable autoinducing loops we needed a very fast and robust method for characterizing parts. For this we have created a cloud based application hosting a genetic algorithm. It also allows the combination of data from multiple experiments across models with overlapping components. This functionality, massively parallelized on the cloud and backed by our own pool of clients, allowed us to find parameters of the parts used in the design.
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'''Our engineered biological abacus counts occurrences of cold shocks.'''
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|You can write a background of your team here.  Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
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[[File:GroningenComic.png|center|500px|]]
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|[[Image:Groningen_logo.png|200px|right|frame]]
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''Tell us more about your project.  Give us background.  Use this as the abstract of your project. Be descriptive but concise (1-2 paragraphs)''
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|align="center"|[[Team:Groningen | Team Example]]
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<!--- The Mission, Experiments --->
 
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<center>'''Our team is based at the University of Groningen in the Netherlands'''</center>
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!align="center"|[[Team:Groningen|Home]]
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!align="center"|[[Team:Groningen/Team|Team]]
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!align="center"|[https://igem.org/Team.cgi?year=2011&team_name=Groningen Official Team Profile]
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<a href="https://2011.igem.org/Team:Groningen/team_overview" onMouseOver="document.groupphoto.src='https://static.igem.org/mediawiki/2011/4/45/TeamGroningenPhoto2.jpg';" onMouseOut="document.groupphoto.src='https://static.igem.org/mediawiki/2011/3/37/TeamGroningenPhoto3.jpg';">
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!align="center"|[[Team:Groningen/Project|Project]]
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<img style="margin: auto; border: 0px double black;" name="groupphoto" src="https://static.igem.org/mediawiki/2011/3/37/TeamGroningenPhoto3.jpg" ></a></div>
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!align="center"|[[Team:Groningen/Parts|Parts Submitted to the Registry]]
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!align="center"|[[Team:Groningen/Modeling|Modeling]]
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<center>(hover your cursor over our team picture for a friendly hello)</center>
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!align="center"|[[Team:Groningen/Notebook|Notebook]]
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!align="center"|[[Team:Groningen/Safety|Safety]]
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{{FooterGroningen2011}}
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!align="center"|[[Team:Groningen/Attributions|Attributions]]
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Latest revision as of 08:58, 28 October 2011


Welcome to the iGEM 2011 Groningen team page

Count coli - a synthetic biological counter

Our project aims to design a genetic device able to count and memorize the occurrences of an input signal. We achieved this by utilizing auto-inducing loops that act as memory units, and an engineered riboregulator acting as an AND gate. This design of the device is modular allowing free change of both input and output signals. Each increase of the counter results in a different output signal. The design allows implementation of any number of memory units, as the AND gate design enables us to extend the system in a hassle-free way. In order to tweak bistable autoinducing loops we needed a very fast and robust method for characterizing parts. For this we have created a cloud based application hosting a genetic algorithm. It also allows the combination of data from multiple experiments across models with overlapping components. This functionality, massively parallelized on the cloud and backed by our own pool of clients, allowed us to find parameters of the parts used in the design.


Our engineered biological abacus counts occurrences of cold shocks.

GroningenComic.png


Our team is based at the University of Groningen in the Netherlands

(hover your cursor over our team picture for a friendly hello)