Team:UQ-Australia

From 2011.igem.org

(Difference between revisions)
 
(13 intermediate revisions not shown)
Line 1: Line 1:
-
<!-- ------------------------------------------------From 2011 Macquarie--------------------------------------------- -->
+
{{:Team:UQ-Australia/Template:Header}}
-
<!-- ------------------------------    Gets rid of the top and bottom iGEM page bits ------------------------------- -->
+
{|style="width:100%;" border="0" cellpadding="10" cellspacing="0"
 +
|rowspan="2"|The human circadian rhythm drives many important processes in the body in accordance with the sleep/wake cycle. A characteristic of this biological clock is the periodic oscillation of gene expression. Current parts in the Registry designed to regulate periodic oscillations of gene expression have shown limited success.
 +
Here we demonstrate the feasibility a biological clock being standardised as a set of BioBrick parts.
-
<html>
+
Our network is controlled by an engineered promoter, Plac/ara, which features both an activator and a repressor domain. This controls the production of downstream genes to activate other inducible promoters, pBAD and GlnAp2, eventually leading to the production of a repressor protein, lacI, which inhibits Plac/ara, resulting in oscillatory expression. This project shows the feasibility of standardising the biological clock in E. coli and grounds further development for applications in regulated drug/hormone delivery and ion channel control.
-
<body>
+
-
<body style="background-color:#772288">
+
-
</body>
+
-
 
+
[[File:Logo facebook.jpg|200px|link=http://www.facebook.com/UQiGEM.2011]]
-
<head>
+
! width="125" |[[File:IGEM basic Logo stylized.png|125x125px|link=https://2011.igem.org]]
-
<style type="text/css">
+
-
body {background-color:#A11F37;}
+
-
 
+
-
<!-- Wiki Hacks -->
+
-
 
+
-
 
+
-
{
+
-
overflow: -moz-scrollbars-vertical !important;
+
-
resize: none;
+
-
background-color: #f5f6f7;
+
-
}
+
-
 
+
-
#top-section {
+
-
height: 20px;
+
-
border-left: none;
+
-
border-right: none;
+
-
}
+
-
 
+
-
#siteSub {
+
-
display:none;
+
-
}
+
-
 
+
-
#search-controls {
+
-
display:none;
+
-
}
+
-
 
+
-
.firstHeading {
+
-
display:none;
+
-
}
+
-
 
+
-
#search-controls {
+
-
margin-top:0px;
+
-
}
+
-
 
+
-
#footer-box {
+
-
display:none;
+
-
}
+
-
 
+
-
 
+
-
 
+
-
#contentSub {
+
-
display:none;
+
-
}
+
-
 
+
-
#siteSub {
+
-
display:none;
+
-
}
+
-
 
+
-
#search-controls {
+
-
display:none;
+
-
}
+
-
 
+
-
.firstHeading {
+
-
display:none;
+
-
}
+
-
 
+
-
#search-controls {
+
-
margin-top:0px;
+
-
}
+
-
 
+
-
#footer-box {
+
-
display:none;
+
-
}
+
-
 
+
-
#top-section {
+
-
height: 20px;
+
-
border-left: none;
+
-
border-right: none;
+
-
}
+
-
 
+
-
.left-menu {
+
-
margin-top:-12px;
+
-
}
+
-
 
+
-
.right-menu {
+
-
margin-top:-12px;
+
-
}
+
-
 
+
-
.left-menu ul {
+
-
border: none;
+
-
}
+
-
 
+
-
#menubar li a {
+
-
color:#8C8984;
+
-
        background-color:transparent;
+
-
}
+
-
 
+
-
#menubar ul {
+
-
color:transparent;
+
-
        background-color:transparent;
+
-
}
+
-
 
+
-
#menubar {
+
-
background-color:transparent;
+
-
font-size:85%;
+
-
line-height:1em;
+
-
position:absolute;
+
-
top:10px;
+
-
white-space:nowrap;
+
-
width:50%;
+
-
z-index:5;
+
-
height:20px;
+
-
overflow:hidden
+
-
 
+
-
}
+
-
 
+
-
.left-menu {
+
-
left:0;
+
-
padding-left: 0px;
+
-
}
+
-
.right-menu  {
+
-
right:0;
+
-
     
+
-
}
+
-
 
+
-
.firstHeading { display:none; }
+
-
}
+
-
 
+
-
#menubar{
+
-
color: #transparent;
+
-
}
+
-
 
+
-
#menubar.right-menu {
+
-
margin-top:-12px;
+
-
}
+
-
 
+
-
.right-menu ul {
+
-
border: none;
+
-
}
+
-
 
+
-
#menubar{
+
-
top:15px;
+
-
z-index:25;
+
-
 
+
-
}
+
-
 
+
-
#menubar {
+
-
background-color:f5f6f7;
+
-
font-size:85%;
+
-
line-height:1em;
+
-
position:absolute;
+
-
top:10px;
+
-
white-space:nowrap;
+
-
width:50%;
+
-
z-index:5;
+
-
height:20px;
+
-
overflow:hidden
+
-
 
+
-
}
+
-
 
+
-
img[src*="/wiki/skins/common/images/wiki.png"]{
+
-
    width:0;
+
-
    height:60px;
+
-
    padding-right:975px;
+
-
    background:#transparent;
+
-
}
+
-
 
+
-
 
+
-
 
+
-
ul#list-nav {
+
-
list-style:none;
+
-
margin:7px 75px 7px;
+
-
 
+
-
padding:0;
+
-
width:1000px
+
-
 
+
-
}
+
-
 
+
-
ul#list-nav li {
+
-
display:inline
+
-
}
+
-
 
+
-
ul#list-nav li a {
+
-
text-decoration:none;
+
-
padding:5px 0;
+
-
width:100px;
+
-
background:#A11F37;
+
-
color:#eee;
+
-
float:left;
+
-
text-align:center;
+
-
border-left:1px solid #fff;
+
-
}
+
-
 
+
-
ul#list-nav li a:hover {
+
-
background:#a2b3a1;
+
-
color:#000
+
-
}
+
-
 
+
-
 
+
-
 
+
-
<!-- End of Wiki Hacks -->
+
-
 
+
-
 
+
-
</body>
+
-
</html>
+
-
 
+
-
 
+
-
<!-- --------------------------------------------From 2009 UQ------------------------------------------------- -->
+
-
<!-- ----------------------------- Gives the background and text colours ------------------------------------- -->
+
-
 
+
-
__NOTOC__
+
-
<html>
+
-
<body style="background-color:#772288">
+
-
 
+
-
<style>
+
-
h1.firstHeading { display: none; }
+
-
 
+
-
p {text-align: justify;}
+
-
 
+
-
a:link { color: #772288; text-decoration: none}
+
-
a:visited { color:#558822; text-decoration: none}
+
-
a:hover { color:#D4A017; text-decoration: none}
+
-
a:active { color:#D4A017; text-decoration: none}
+
-
 
+
-
#bodyContent { padding: 10px auto; width: 910px; margin: auto; clear: none; }
+
-
 
+
-
table#team_members { text-align: justify; border: 0; }
+
-
table#team_members h2, table#team_members h3 { clear: both; }
+
-
 
+
-
 
+
-
</style>
+
-
 
+
-
 
+
-
<!-- ------------------------------------From DTU-Denmark-2 2011---------------------------------------------- -->
+
-
<!-- ---------------------------------------- Navigation Bar ------------------------------------------------- -->
+
-
 
+
-
<head>
+
-
<style type="text/css">
+
-
 
+
-
/* Layout */
+
-
@import "http://users.skumleren.net/gumle/dropdown/css/dropdown/dropdown.css";
+
-
 
+
-
/* Theme */
+
-
@import "http://users.skumleren.net/gumle/dropdown/css/dropdown/themes/default/default.css";
+
-
 
+
-
ul.dropdown li {
+
-
background-color: #000000;
+
-
color: #FFFFFF;
+
-
width: 99.7px;
+
-
text-align: center;
+
-
}
+
-
 
+
-
ul.dropdown li.hover,
+
-
ul.dropdown li:hover {
+
-
background-color: #772288;
+
-
color: #FFFFFF;;
+
-
}
+
-
ul.dropdown a:link,
+
-
ul.dropdown a:visited { color: #D4A017;; text-decoration: none; }
+
-
ul.dropdown a:hover { color: #FFFFFF;; text-decoration: underline; }
+
-
ul.dropdown a:active { color: #FFFFFF;; }
+
-
 
+
-
ul.dropdown ul  * {
+
-
width: 109.7px;
+
-
}
+
-
 
+
-
 
+
-
 
+
-
.ideasList{
+
-
margin-bottom:30px
+
-
}
+
-
 
+
-
ul#sub {
+
-
margin:0px;
+
-
padding:0px;
+
-
font-size:11px;
+
-
list-style-image:none;
+
-
list-style-type:none;
+
-
 
+
-
}
+
-
 
+
-
#sub li { margin-bottom:20px;}
+
-
 
+
-
#sub li a {
+
-
color:#FFFFFF;
+
-
text-decoration:underline;
+
-
}
+
-
 
+
-
#sub li a:hover {
+
-
text-decoration:none;
+
-
}
+
-
 
+
-
li.subsubmenu {
+
-
        position: relative;
+
-
        left: 3px;
+
-
        top: -3px;
+
-
}
+
-
 
+
-
 
+
-
 
+
-
</style>
+
-
<! -- END of style sheet -->
+
-
 
+
-
</head>
+
-
<body>
+
-
 
+
-
<!-- Beginning of compulsory code below -->
+
-
 
+
-
 
+
-
<ul id="nav" class="dropdown dropdown-horizontal">
+
-
<li><a href="https://2011.igem.org/Team:UQ-Australia">Home</a></li>
+
-
 
+
-
<li class="dir"><a href="https://2011.igem.org/Team:UQ-Australia/Team">Team</a>
+
-
              <ul>
+
-
                        <li><a href="https://2011.igem.org/Team:UQ-Australia/Team">Students</a></li>
+
-
                        <li><a href="https://2011.igem.org/Team:UQ-Australia/Team">Supervisors</a></li>
+
-
<li><a href="https://2011.igem.org/Team:UQ-Australia/Team">Gallery</a></li>
+
-
        </ul>
+
-
</li>
+
-
 
+
-
<li class="dir"><a href="https://2011.igem.org/Team:UQ-Australia/Project">Details</a>
+
-
                <ul>
+
-
<li><a href="https://2011.igem.org/Team:UQ-Australia/Project">Details</a></li>
+
-
<li><a href="https://2011.igem.org/Team:UQ-Australia/Project">Experiemntal work</a></li>
+
-
                        <li><a href="https://2011.igem.org/Team:UQ-Australia/Project">Modelling</a></li>
+
-
                        <li><a href="https://2011.igem.org/Team:UQ-Australia/Project">Safety</a></li>
+
-
                        <li><a href="https://2011.igem.org/Team:UQ-Australia/Project">Human Practices</a></li>
+
-
        </ul>
+
-
</li>
+
-
 
+
-
        <li class="dir"><a href="https://2011.igem.org/Team:UQ-Australia/Parts">Parts</a></li>
+
-
 
+
-
        <li class="dir"><a href="https://2011.igem.org/Team:UQ-Australia/Data">Data</a></li>
+
-
 
+
-
<li class="dir"><a href="https://2011.igem.org/Team:UQ-Australia/Modeling">Modelling</a>
+
-
<ul>
+
-
<li><a href="https://2011.igem.org/Team:UQ-Australia/Modeling">Kinetics</a></li>
+
-
<li><a href="https://static.igem.org/mediawiki/2011/d/d6/PHYS3900-LitReview-Ann-PrettiedUp.pdf">Synchronisation</a></li>
+
-
                        <li><a href="https://2011.igem.org/Team:UQ-Australia/Modeling">Microscopy</a></li>
+
-
</ul>
+
-
</li>
+
-
 
+
-
        <li class="dir"><li><a href="https://2011.igem.org/Team:UQ-Australia/Notebook">Notebook</a></li>
+
-
 
+
-
<ul>
+
-
<li><a href="https://2011.igem.org/Team:UQ-Australia/Notebook">Time 1</a></li>
+
-
<li><a href="https://2011.igem.org/Team:UQ-Australia/Notebook">Time 2</a></li>
+
-
                        <li><a href="https://2011.igem.org/Team:UQ-Australia/Notebook">Time 3</a></li>
+
-
</ul>
+
-
</li>
+
-
 
+
-
        <li><a href="https://2011.igem.org/Team:UQ-Australia/Safety">Safety</a></li>
+
-
 
+
-
<li class="dir"><a href="https://2011.igem.org/Team:UQ-Australia/Human_Practices">Hunman Practices</a>
+
-
                <ul>
+
-
                        <li><a href="https://2011.igem.org/Team:UQ-Australia/Human_Practices">Outreach</a></li>
+
-
                        <li><a href="https://2011.igem.org/Team:UQ-Australia/Human_Practices">Patenting</a></li>
+
-
                </ul>
+
-
</li>
+
-
 
+
-
<li class="dir"><a href="https://2011.igem.org/Team:UQ-Australia/Project">Attributions</a></li>
+
-
+
-
</ul>
+
-
 
+
-
<br>
+
-
 
+
-
 
+
-
</head>
+
-
 
+
-
<!-- ---------------------------------------- From 2011 Harvard ---------------------------------------------- -->
+
-
<!-- ---------------------------------------- For the image bar ---------------------------------------------- -->
+
-
+
-
<script src="http://ajax.googleapis.com/ajax/libs/jquery/1.4.2/jquery.min.js"></script>
+
-
<script src="http://www.people.fas.harvard.edu/~nnaushad/galleryview-3.0b1/jquery.galleryview-3.0.min.js"></script>
+
-
<script src="http://www.people.fas.harvard.edu/~nnaushad/galleryview-3.0b1/jquery.timers-1.2.js"></script>
+
-
<script src="http://www.people.fas.harvard.edu/~nnaushad/galleryview-3.0b1/ajquery.easing.1.3.js"></script>
+
-
+
-
<link rel="stylesheet" href="jquery.galleryview-3.0.css" type="text/css" >
+
-
<script>
+
-
$(document).ready(function(){
+
-
$('#gallery').galleryView({
+
-
panel_width: 920,
+
-
panel_height: 253,
+
-
frame_width: 50,
+
-
frame_height: 50,
+
-
panel_animation: true,
+
-
transition_interval:3500,
+
-
pause_on_hover: true
+
-
});
+
-
});
+
-
</script>
+
-
</body>
+
-
 
+
-
<!----------------GALLERY DIV---------------->
+
-
+
-
<div class="whitebox" style="margin-top: 20px;">
+
-
<ul id="gallery">
+
-
+
-
<li><img src="https://static.igem.org/mediawiki/2009/a/a6/UQ_banner.jpg" /></li>
+
-
<li><img src="https://static.igem.org/mediawiki/2009/a/a6/UQ_banner.jpg" /></li>
+
-
<li><img src="https://static.igem.org/mediawiki/2009/a/a6/UQ_banner.jpg" /></li>
+
-
<li><img src="https://static.igem.org/mediawiki/2009/a/a6/UQ_banner.jpg" /></li>
+
-
                                <li><img src="https://static.igem.org/mediawiki/2009/a/a6/UQ_banner.jpg" /></li>
+
-
<li><img src="https://static.igem.org/mediawiki/2009/a/a6/UQ_banner.jpg" /></li>
+
-
<li><img src="https://static.igem.org/mediawiki/2009/a/a6/UQ_banner.jpg" /></li>
+
-
                                <li><img src="https://static.igem.org/mediawiki/2009/a/a6/UQ_banner.jpg" /></li>
+
-
 
+
-
+
-
</ul>
+
-
        </div>
+
-
<br>
+
-
 
+
-
 
+
-
</html>
+
-
 
+
-
<!-- -------------------------- ------------------------Text-------------------------------------------------- -->
+
-
 
+
-
 
+
-
{|align="justify"
+
-
|
+
-
|[[Image:UQ-Australia_logo.png|200px|right|frame]]  
+
|-
|-
-
|
+
|[[File:UQ-Australia_logo_2011.png|125x125px|link=https://2011.igem.org/Team:UQ-Australia]]
 +
|}
-
The human circadian rhythm drives many important processes in the body in accordance with the sleep/wake cycle. A characteristic of this biological clock is the periodic oscillation of gene expression. Current parts in the Registry designed to regulate periodic oscillations of gene expression have shown limited success.
+
'''NB: wiki best viewed on Chrome, Firefox or Safari.'''
-
Here we demonstrate a biological clock being standardised as a set of BioBrick parts.
+
-
 
+
-
Our network is controlled by an engineered promoter, Plac/ara, which features both an activator and a repressor domain. This controls the production of downstream genes to activate other inducible promoters, pBAD and GlnAp2, eventually leading to the production of a repressor protein, lacI, which inhibits Plac/ara, resulting in oscillatory expression. This project shows the feasibility of standardising the biological clock in E. coli and grounds further development for applications in regulated drug/hormone delivery and ion channel control.
+
-
 
+
-
 
+
-
 
+
-
Find us on [http://www.facebook.com/pages/UQ-iGEM-2011/174356539258535 Facebook]!
+
-
 
+
-
 
+
-
|[[Image:UQ-Australia_team.png|right|frame|Your team picture]]
+
-
|-
+
-
|
+
-
|align="center"|[[Team:UQ-Australia | Team Example]]
+
-
|}
+

Latest revision as of 00:32, 6 October 2011




The human circadian rhythm drives many important processes in the body in accordance with the sleep/wake cycle. A characteristic of this biological clock is the periodic oscillation of gene expression. Current parts in the Registry designed to regulate periodic oscillations of gene expression have shown limited success.

Here we demonstrate the feasibility a biological clock being standardised as a set of BioBrick parts.

Our network is controlled by an engineered promoter, Plac/ara, which features both an activator and a repressor domain. This controls the production of downstream genes to activate other inducible promoters, pBAD and GlnAp2, eventually leading to the production of a repressor protein, lacI, which inhibits Plac/ara, resulting in oscillatory expression. This project shows the feasibility of standardising the biological clock in E. coli and grounds further development for applications in regulated drug/hormone delivery and ion channel control.

Logo facebook.jpg

IGEM basic Logo stylized.png
UQ-Australia logo 2011.png


NB: wiki best viewed on Chrome, Firefox or Safari.

Retrieved from "http://2011.igem.org/Team:UQ-Australia"