Team:Valencia

From 2011.igem.org

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<div class=col_left_top>Water Colicin Cleaner: disinfected water by E. coli</div><!-- fin clase col_left_top-->
<div class=col_left_top>Water Colicin Cleaner: disinfected water by E. coli</div><!-- fin clase col_left_top-->
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<div class=col_left_center>Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in Escherichia coli. As a proof of concept we have chosen to aim for enterobacteria, focusing on E. coli contaminated water, as a proxy of fecal water. The cleaning of E. coli will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.
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<p>Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in Escherichia coli. As a proof of concept we have chosen to aim for enterobacteria, focusing on E. coli contaminated water, as a proxy of fecal water. The cleaning of E. coli will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.</p>
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We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.
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<p>We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.</p><
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W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases. </div><!-- fin clase col_left_top-->
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<p>W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.</p> </div><!-- fin clase col_left_top-->
<div class=col_left_bottom><img src="https://static.igem.org/mediawiki/2011/8/81/Valencia_logo.jpg"></div><!-- fin clase col_left_top-->
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Revision as of 10:43, 21 September 2011



Water Colicin Cleaner: disinfected water by E. coli

Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in Escherichia coli. As a proof of concept we have chosen to aim for enterobacteria, focusing on E. coli contaminated water, as a proxy of fecal water. The cleaning of E. coli will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.

We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.

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W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.

Who we are