Team:Valencia
From 2011.igem.org
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<div class=col_left_top>Water Colicin Cleaner: disinfected water by E. coli</div><!-- fin clase col_left_top--> | <div class=col_left_top>Water Colicin Cleaner: disinfected water by E. coli</div><!-- fin clase col_left_top--> | ||
- | <div class=col_left_center>Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in Escherichia coli. As a proof of concept we have chosen to aim for enterobacteria, focusing on E. coli contaminated water, as a proxy of fecal water. The cleaning of E. coli will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media. | + | <div class=col_left_center> |
+ | <p>Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in Escherichia coli. As a proof of concept we have chosen to aim for enterobacteria, focusing on E. coli contaminated water, as a proxy of fecal water. The cleaning of E. coli will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.</p> | ||
- | We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality. | + | <p>We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.</p>< |
- | W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases. </div><!-- fin clase col_left_top--> | + | <p>W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.</p> </div><!-- fin clase col_left_top--> |
<div class=col_left_bottom><img src="https://static.igem.org/mediawiki/2011/8/81/Valencia_logo.jpg"></div><!-- fin clase col_left_top--> | <div class=col_left_bottom><img src="https://static.igem.org/mediawiki/2011/8/81/Valencia_logo.jpg"></div><!-- fin clase col_left_top--> | ||
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- | <img src="https://static.igem.org/mediawiki/ | + | <img src="https://static.igem.org/mediawiki/2011/b/b1/Valencia_Upvtranspa.gif"/ width="150"/> |
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- | <img src="https://static.igem.org/mediawiki/ | + | <img src="https://static.igem.org/mediawiki/2011/2/25/Valencia_Ucvtranspa.gif" width="200" /> |
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<div class=col_right_center> | <div class=col_right_center> | ||
- | <img src="https://static.igem.org/mediawiki/ | + | <img src="https://static.igem.org/mediawiki/2011/7/7a/Valencia_Uvtrasnpa.gif" width="150" /> |
</div><!-- fin clase col_right_center--> | </div><!-- fin clase col_right_center--> | ||
Revision as of 10:43, 21 September 2011
Water Colicin Cleaner is a biological alternative for disinfecting contaminated water using synthetic biology. We kill targeted pathogens by means of antimicrobial peptides in Escherichia coli. As a proof of concept we have chosen to aim for enterobacteria, focusing on E. coli contaminated water, as a proxy of fecal water. The cleaning of E. coli will be possible thanks to the colicin protein. The activity of these proteins will be controlled by a biological pH-stat, using light-driven cyanobacteria to control pH of the media.
We will deliver a DIY kit as a prototype platform for killing pathogens responsible of diseases such as cholera, diarrhea and typhoid fever, ending with more than 2 million deaths in the last year according to the 2011 WHO Guidelines for Drinking-Water Quality.
<W.C. Cleaner is an effective, low-cost device, that will help people that struggle to find pathogen-free drinking water avoid important diseases.