Name [65]
| Name [15]
| Name[25]
| I-A
| I-B
| I-C
| I-D
| I-E
| I-F
| II-A
| II-B
| III-A
| III-B
| I-U
| III-U
| U
| COG
| TIGR
| Ramp [65]
| cascade-like complex [65]
| putative function
| grouping [75]
|
| cas_HTH | | | | | | | | | | | | | | | | | | | |
|
cas1 | cas1 | cas1 | y | y | y | y | y | y | y | y | y | y | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1518 1518] | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR00287 00287] | | | Nuclease [65] |
|
cas10 | cmr2 | | | | | | | | | | y | y | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1353 1353] | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR02577 02577] | | y | Polymerase [65] |
|
csm1 | | | | | | | | | | y | y | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR02578 02578] | | y |
|
csx11 | | | | | | | | | | y | y | | | | | | y |
|
cas10d | csc3 | | | | | y | | | | | | | | | | | | y | |
|
cas2 | cas2 | cas2 | y | y | y | y | y | y | y | y | y | y | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1343 1343], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG3512 3512] | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01573 01573] | | | |
|
cas3' | cas3 | cas3 | y | y | y | y | y | y | | | | | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1203 1203] | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01587 01587] | | | Helicase, nuclease [15] |
|
cas3 | | | y | y | | | | | | | | | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG2254 2254] | | | | |
|
cas4 | cas4 | | y | y | y | y | | | | y | | | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1468 1468] | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR00372 00372] | | | RecB exonuclease [65][8] |
|
csa1 | | y | y | y | y | | | | y | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01896 01896] | | |
|
cas5 | cas5d | casD | y | y | y | | y | | | | | | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1688 1688] | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01876 01876] | y | y | N-terminal domain [15], crRNA processing [65] | cas5
|
cas5e | y | y | y | | y | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01868 01868] | y | y | cas5
|
cas5h | y | y | y | | y | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR02592 02592] | y | y | cas5
|
cas5t | y | y | y | | y | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01895 01895] | y | y | cas5
|
cmx5 | y | y | y | | y | | | | | | | | | | y | y | cas5
|
csa5a | y | y | y | | y | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01874 01874] | y | y | cas5
|
cas6 | cas6 | | y | y | | y | | | | | y | y | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1583 1583], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG5551 5551] | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01877 01877] | y | | crRNA processing [65] | cas6
|
cmx6 | | y | y | | y | | | | | y | y | | | | | y | | cas6
|
cas6e | cse3 | casE | | | | | y | | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01907 01907] | y | | cas6
|
cas6f | csy4 | | | | | | | y | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR02563 02563] | y | | cas6
|
cas7 | csa2 | casC | y | y | y | | y | | | | | | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1857 1857], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG3649 3649] | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR02583 02583] | y | y | Regulation [15] | cas7
|
csd2 | y | y | y | | y | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR02589 02589] | y | y | cas7
|
cse4 | y | y | y | | y | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01869 01869] | y | y | cas7
|
csh2 | y | y | y | | y | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR02590 02590] | y | y | cas7
|
cst2 | y | y | y | | y | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR02585 02585] | y | y | cas7
|
cas8a1 | CXXC-CXXC | | y | | | | | | | | | | | | | | | | y | |
|
cmx1 | | y | | | | | | | | | | | | | | | | y | |
|
cst1 | | y | | | | | | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01908 01908] | | y | |
|
csx13 | | y | | | | | | | | | | | | | | | | y | |
|
csx8 | | y | | | | | | | | | | | | | | | | y | |
|
cas8a2 | csa4 | | y | | | | | | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01914 01914] | | y | |
|
csx9 | | y | | | | | | | | | | | | | | | | y | |
|
cas8b | TM1802 | | | y | | | | | | | | | | | | | | | y | |
|
csh1 | | | y | | | | | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR02591 02591] | | y | |
|
cas8c | csd1 | | | | y | | | | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01863 01863] | | y | |
|
csp2 | | | | y | | | | | | | | | | | | | | y | |
|
cas9 | csn1 | | | | | | | | y | y | | | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG3513 3513] | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01865 01865] | | | HNH endonuclease [15] |
|
csx12 | | | | | | | | y | y | | | | | | | | |
|
cmr1 | cmr1 | | | | | | | | | | | y | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1367 1367] | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01894 01894] | y | y | | cas7
|
cmr3 | cmr3 | | | | | | | | | | | y | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1769 1769] | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01888 01888] | y | y | | cas5
|
cmr4 | cmr4 | | | | | | | | | | | y | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1336 1336] | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR02580 02580] | y | y | | cas7
|
cmr5 | cmr5 | | | | | | | | | | | y | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG3337 3337] | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01881 01881] | | y | |
|
cmr6 | cmr6 | | | | | | | | | | | y | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1604 1604] | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01898 01898] | y | y | | cas7
|
csa5 | csa5 | | y | | | | | | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01878 01878] | | y | |
|
csaX | csaX | | | | | | | | | | | | | y | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR03876 03876] | | | |
|
csb1 | GSU0053 | | | | | | | | | | | | y | | | | | y | | |
|
csb2 | | | | | | | | | | | | | y | | | | | y | | |
|
csb3 | | | | | | | | | | | | | y | | | | | y | | |
|
csc1 | csc1 | | | | | | | | | | | | | | | | | y | y | | cas5
|
csc2 | csc2 | | | | | | | | | | | | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1337 1337] | | y | y | | cas7
|
cse1 | cse1 | casA | | | | | y | | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR02547 02547] | | y | |
|
cse2 | cse2 | casB | | | | | y | | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR02548 02548] | | y | |
|
csf1 | csf1 | | | | | | | | | | | | | | y | | | | | |
|
csf2 | csf2 | | | | | | | | | | | | | | y | | | y | | | cas7
|
csf3 | csf3 | | | | | | | | | | | | | | y | | | y | | |
|
csf4 | csf4 | | | | | | | | | | | | | | y | | | | | |
|
csm2 | csm2 | | | | | | | | | | y | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01870 01870] | | y | |
|
csm3 | csc2 | | | | | | | | | | y | | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1337 1337] | | y | y | | cas7
|
csm3 | | | | | | | | | | y | | | | | | y | y | | cas7
|
csm4 | csm4 | | | | | | | | | | y | | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1567 1567] | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01903 01903] | y | y | | cas5
|
csm5 | csm5 | | | | | | | | | | y | | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1332 1332] | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01899 01899] | y | y | | cas7
|
csm6 | APE2256 | | | | | | | | | | y | | | | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1517 1517] | | | | transcription regulation [65] |
|
csm6 | | | | | | | | | | y | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR02672 02672] | | |
|
csn2 | csn2 | | | | | | | | y | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01866 01866] | | | |
|
csx1 | DXTHG | | | | | | | | | | | | | y | | [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1517 1517], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG4006 4006] | | | | Helix-turn-helix, transcription regulation [15] |
|
NE0113 | | | | | | | | | | | | | y | | | | |
|
TIGR02710 | | | | | | | | | | | | | y | | | | |
|
csa3 | | | | | | | | | | | | | y | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR01884 01884] | | |
|
csx1 | | | | | | | | | | | | | y | | | | |
|
csx2 | | | | | | | | | | | | | y | | | | |
|
csx10 | csx10 | | | | | | | | | | | | y | | | | | y | | |
|
csx14 | | | | | | | | | | | | | y | | | | | | | |
|
csx15 | | | | | | | | | | | | | | | | | | | | |
|
csx16 | VVA1548 | | | | | | | | | | | | | y | | | | | | |
|
csx17 | | | | | | | | | | | | | y | | | | | | | |
|
csx3 | csx3 | | | | | | | | | | | | | y | | | | | | |
|
csy1 | csy1 | | | | | | | y | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR02564 02564] | | y | |
|
csy2 | csy2 | | | | | | | y | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR02565 02565] | y | y | | cas5
|
csy3 | csy3 | | | | | | | y | | | | | | | | | [http://www.ebi.ac.uk/interpro/ISignature?ac=TIGR02566 02566] | | y | | cas7
|