Team:Yale/Safety

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1. Based on our experimental design, our project can be categorized as fairly low-risk. With highly experienced graduate and faculty advisors guiding us, the probability of significant safety issues or random error was largely diminished. In addition, our iGEM project did not involve working with any infectious host organisms or chemicals. We also carefully engineered our systems, so that if one or several bioparts changed their function or stop working as intended, then consequences would be minimized. Thus, with low hazard and low probability, our project overall had low safety risks.


2. Our BioBrick submissions do not pose any sort of significant safety issues.


3. Yale University has its own institutional review board, and our project underwent rigorous scrutinization from a range of faculty members in the Molecular Biochemistry and Biophysics Department. We received approval from all overseeing groups.


4. In terms of general safety issues, our team believes that the best case practice is comprehensive documentation. With more detailed and better characterized parts, synthetic biology can be an extremely controlled and safe experience, even for young undergraduate researchers!



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