Team:Wageningen UR/Project/ModelingProj1
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in which tau represents the time step. It can be seen that the function takes the history of the system into account, since the production of the proteins depend on the past concentration of internal AHL as in: [[File:Equations3_hasty_WUR.png]]. | in which tau represents the time step. It can be seen that the function takes the history of the system into account, since the production of the proteins depend on the past concentration of internal AHL as in: [[File:Equations3_hasty_WUR.png]]. | ||
- | For the first simulations, the same values for the parameters were used as in the cited paper and can be found in the [http://www.nature.com/nature/journal/v463/n7279/suppinfo/nature08753.html supplementary information]. To get graphs representing optimal oscillations, the matlab tool allows the flow rate and cell density to be varied over a range of values. | + | For the first simulations, the same values for the parameters were used as in the cited paper and can be found in the [http://www.nature.com/nature/journal/v463/n7279/suppinfo/nature08753.html supplementary information]. To get graphs representing optimal oscillations, the matlab tool allows the flow rate and cell density to be varied over a range of values. Figure 2 shows the GUI of the matlab tool created for this purpose. It allows the user to enter the range in which the variables should be varied. The tool then iterates over the values and produces graphs of all combinations possible for that range of values. Figure 3 shows an example output of the tool. |
The first observation from the model was that the flow rate necessary to obtain oscillations has to be very slow. Since the device used for our system has larger dimensions as the microfluidic device used by Danino et al. the flow rates in the velocities required couldn't be achieved by varying height differences alone. Further information can be found in the information about the [[Team:Wageningen_UR/Project/Devices| devices.]] | The first observation from the model was that the flow rate necessary to obtain oscillations has to be very slow. Since the device used for our system has larger dimensions as the microfluidic device used by Danino et al. the flow rates in the velocities required couldn't be achieved by varying height differences alone. Further information can be found in the information about the [[Team:Wageningen_UR/Project/Devices| devices.]] | ||
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Revision as of 22:50, 16 September 2011