Team:UNITS Trieste/Acknowledgements
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+ | <span>SINBIOME ACKNOWLEDGEMENTS</span> | ||
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<b>Thanks to Synbiome we had the chance to involve scientists originally unrelated to the field of synthetic biology as our instructors. They believed so much our project that we’re not only working at Synbiome in a competitive optical but mostly looking forward to reach a publication at the end of the year.</b><br/> | <b>Thanks to Synbiome we had the chance to involve scientists originally unrelated to the field of synthetic biology as our instructors. They believed so much our project that we’re not only working at Synbiome in a competitive optical but mostly looking forward to reach a publication at the end of the year.</b><br/> | ||
These rows have been written only to give you all the feelings that this experience has meant for us, we really hope that you will enjoy Synbiome.<br/> | These rows have been written only to give you all the feelings that this experience has meant for us, we really hope that you will enjoy Synbiome.<br/> | ||
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+ | <b>Looking for Boston</b> | ||
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+ | During the Regional Jamboree in Amsterdam we focused our attention in collecting any kind of feedbacks from everybody: judges, instructors, advisors and other igemmers.<br/> | ||
+ | This has been really useful also to plan our work during this supplementary month.<br/> | ||
+ | Looking for Boston we decided to change the genetic circuit inside the bacterial strain A.<br/> | ||
+ | At the beginning of this experience we believed that forcing a strong mutualism between the two bacterial strains would represent the best way to build a stable consortium. Following this purpose we designed for Amsterdam a bacterial strain A, which in response to OXOC8 produces OXOC12 and glucosidase and a bacterial strain B, which produces OXOC8 and glucosidase in presence of OXOC12. Both A and B are not sensible to their own language and so A needs B and vice versa. This kind of circuit guarantees a strong mutualism but will also generate a kind of useless redundancy in which both A and B produce the same reward for the whole system.<br/> | ||
+ | Moreover this genetic circuit needs an initial external injection of or OXOC8 or OXOC12 to start the system.<br/> | ||
+ | Our feelings suggested us to keep Symbiome simple and more effective associating to each characters a specific and unique task.<br/> | ||
+ | On these new evidences we decided to give to cell A the role of starting up the system by constitutively producing OC12, leaving to cells B and C the production of the rewards, respectively the beta-glucosidase and the secreted beta-lactamase.<br/> | ||
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- | <td class="logo"><a title="ICGEB" target="_blank" href="http://www.icgeb.org/ | + | <td class="logo"><a title="ICGEB" target="_blank" href="http://www.icgeb.org/mauro-giacca.html"><img src="https://static.igem.org/mediawiki/2011/a/ae/Units-attr-icgeb.jpg"></a></td> |
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<span class="attr-name"><b>Mauro Giacca,</b> Director, ICGEB Trieste Component, Group Leader</span><br/> | <span class="attr-name"><b>Mauro Giacca,</b> Director, ICGEB Trieste Component, Group Leader</span><br/> | ||
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- | <td class="logo"><a title="ICGEB" target="_blank" href="http://www.icgeb.org/ | + | <td class="logo"><a title="ICGEB" target="_blank" href="http://www.icgeb.org/vittorio-venturi.html"><img src="https://static.igem.org/mediawiki/2011/a/ae/Units-attr-icgeb.jpg"></a></td> |
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<span class="attr-name"><b>Vittorio Venturi,</b> Group Leader</span><br/> | <span class="attr-name"><b>Vittorio Venturi,</b> Group Leader</span><br/> | ||
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<span class="attr-name"><b>Sandor Pongor,</b> Group leader</span><br/> | <span class="attr-name"><b>Sandor Pongor,</b> Group leader</span><br/> | ||
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- | <td class="logo"><a title=" | + | <td class="logo"><a title="Dsv" target="_blank" href="http://dsv.units.it"><img src="https://static.igem.org/mediawiki/2011/f/fb/Units-logodsv.png"/></a></td> |
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<span class="attr-name"><b>Dr. Riccardo Sgarra</b></span><br/> | <span class="attr-name"><b>Dr. Riccardo Sgarra</b></span><br/> | ||
- | <span class="attr-descr">Life Sciences | + | <span class="attr-descr">Department of Life Sciences, University of Trieste, Trieste, Italy</span> |
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- | <td>Mass | + | <td>Mass Spectrometry</td> |
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<span class="attr-name"><b style="padding:0px;">Maddalena Fragnito</b></span> | <span class="attr-name"><b style="padding:0px;">Maddalena Fragnito</b></span> |
Latest revision as of 14:51, 28 October 2011
SINBIOME ACKNOWLEDGEMENTS