Team:SouthBend-Mishawaka-HS

From 2011.igem.org

Revision as of 21:38, 21 April 2011 by BigItalianGuy (Talk | contribs)


This is a template page. READ THESE INSTRUCTIONS.
You are provided with this team page template with which to start the iGEM season. You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki. You can find some examples HERE.
You MUST have a team description page, a project abstract, a complete project description, a lab notebook, and a safety page. PLEASE keep all of your pages within your teams namespace.



You can write a background of your team here. Give us a background of your team, the members, etc. Or tell us more about something of your choosing.
File:SouthBend-Mishawaka-HS logo.png
200px

Tell us more about your project. Give us background. Use this as the abstract of your project. Be descriptive but concise (1-2 paragraphs)

File:SouthBend-Mishawaka-HS team.png
Your team picture
Team Example


Home Team Official Team Profile Project Parts Submitted to the Registry Modeling Notebook Safety Attributions


Banner
pH Sensor
pH Sensor
A sensor of proton concentration (pH). Activates in a high pH environment.
Attachment
Attachment
Attachment to the small intestine.
Urea
Clearance of Urea
A Urea clearance device.
Guanidine
Clearance of Guanidine
The device managing the clearance of guanidino compounds.
Phosphate
Clearance of Phosphate
A Phosphate clearance and balance device.
Time Regulation
Time Regulation
Using oscillators to measure time, it enables detachment from the small intestine after a certain amount of time.
Team:NYMU-Taipei/Links



BacToKidney - Toward a better quality of life.


Goal:

  • Use designer bacteria to replace a hemodialysis machine to remove (filter out) toxic waste for treating kidney failure.


Why is it an interesting problem?

  • Approximately 1.3 million people globally have chronic kidney failure that requires either renal transplantation or dialysis - for such patients, the established treatment is hemodialysis
  • The mortality rate of patients undergoing maintenance hemodialysis remains unacceptably high.
  • An extremely high morbidity and a relatively low quality of life (due in part to a high level of dependence and unemployment) and high cost have also been observed.


Our Design:

  • After ingesting our BacToKidney capsule, it passes the through stomach without taking any action, nor being digested, and proceeds to the small intestine. Once in the small intestine, the pH Sensor detects the change in pH and activates the clearance processes of Urea, Phosphate, and Guanidine from the body. To allow itself more time to perform its tasks, the pH Sensor also activates the Attachment process, making the capsule attach itself to the small intestine. After a pre-selected amount of time has passed (controlled by the time regulating oscillators), the capsule detaches itself from the small intestine and exits the body.


The parts our project is made up of:

Team:NYMU-Taipei/News

Team:NYMU-Taipei/Footer

Retrieved from "http://2011.igem.org/Team:SouthBend-Mishawaka-HS"