Modeling

Predicting how our systems will react during experiments required precise modeling. Like most synthetic biology projects, we had to create simulations of our gene regulation networks using Matlab. We also had to think carefully about diffusion of very few molecule in a cell and to propose models of diffusion (wether it is passive, active or "semi-active") in nanotubes to correcly model our systems. Those simulations were done using Matlab, Maya and a lot of reflexion.

Image here	What is modeling in synthetic biology? You can finde here an introduction to our methods and the general idea behind most models in gene network.
Image here	Our Hypotheses Because of the specificities of our project, we had to adapt the "classic" model to better represent our current situation. On top of that we made and justified a few other hypotheses detailed in this section.
Image here	Modeling our designs Models predicting the behaviour of our designs are detailled in this section.
Image here	Tension & assisted diffusion We propose here a model explaining how diffusion through nanotubes could be "assisted" by the tension differential between cell walls.

Team:Paris Bettencourt/Modeling

From 2011.igem.org

Modeling