Team:ETH Zurich/Modeling/Analytical Approximation

From 2011.igem.org

(Difference between revisions)
(Kolmogorov-Petrovsky-Piskounov Equation)
(Kolmogorov-Petrovsky-Piskounov Equation)
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We derived the gradient formation dynamics analytically already in the [[Team:ETH_Zurich/Modeling/Microfluidics#Model|reaction-diffusion model]]. However, there we only solved the resulting partial differential equation numerically. '''Here, we are going to venture forth and give a suitable analytical approximation!'''
We derived the gradient formation dynamics analytically already in the [[Team:ETH_Zurich/Modeling/Microfluidics#Model|reaction-diffusion model]]. However, there we only solved the resulting partial differential equation numerically. '''Here, we are going to venture forth and give a suitable analytical approximation!'''
== Kolmogorov-Petrovsky-Piskounov Equation ==
== Kolmogorov-Petrovsky-Piskounov Equation ==
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[[File:ETH-AcAl-Reaction-Diffusion.png|317px|center|thumb|General partial differential equation for an acetaldehyde reaction-diffusion system. '''D(AcAl(x,z),z)''' is the diffusive term, '''R(AcAl(x,z))''' is the uniform (independent of the spatial z coordinate) reaction term.]]
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In mathematics, the problem posed by general reaction-diffusion systems form is known as the '''Kolmogorov-Petrovsky-Piskounov Equation'''. In the case of acetaldehyde as diffusing and reacting molecule, the equation has the following general structure:
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In mathematics, the problem posed by general reaction-diffusion systems of this form is known as the '''Kolmogorov-Petrovsky-Piskounov Equation'''.
+
[[File:ETH-AcAl-Reaction-Diffusion.png|317px|center|thumb|General Kolmogorov-Petrovsky-Piskounov partial differential equation for an acetaldehyde reaction-diffusion system. '''D(AcAl(x,z),z)''' is the diffusive term, '''R(AcAl(x,z))''' is the uniform (independent of the spatial z coordinate) reaction term.]]
== Dead Zone Concept ==
== Dead Zone Concept ==

Revision as of 18:12, 27 October 2011

Can you feel the smoke tonight?
 

Contents

Analytical Approximation


GFP Band: Dimensionless Model

1. Dimensionless Species

We nondimensionalized all species occurring in the equations for the GFP band circuit.

ETHZ-Dimensionless-Species.png


2. Dimensionless Equations

The dimensionless equations for the dynamics of the band-generating system then read

ETHZ-Dimensionless-Band.png

3. Steady State

ETHZ-Dimensionless-Band-SteadyState.png

4. Dimensionless Groupings

The equation system can be simplified by introducing the following dimensionless groupings:

ETHZ-Dimensionless-Groupings.png


This yields the final equations for steady state:

ETHZ-Dimensionless-Band-SteadyState-Final.png


Gradient Approximation

We derived the gradient formation dynamics analytically already in the reaction-diffusion model. However, there we only solved the resulting partial differential equation numerically. Here, we are going to venture forth and give a suitable analytical approximation!

Kolmogorov-Petrovsky-Piskounov Equation

In mathematics, the problem posed by general reaction-diffusion systems form is known as the Kolmogorov-Petrovsky-Piskounov Equation. In the case of acetaldehyde as diffusing and reacting molecule, the equation has the following general structure:

General Kolmogorov-Petrovsky-Piskounov partial differential equation for an acetaldehyde reaction-diffusion system. D(AcAl(x,z),z) is the diffusive term, R(AcAl(x,z)) is the uniform (independent of the spatial z coordinate) reaction term.

Dead Zone Concept

Analytical Solution


References


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