Modelling the Sphereactor

Structure of a Pdu Microcompartment

One approach to modelling we decided to take, was to investigate the structure of a Pdu microcompartment and its size relative to an E.coli chassis. Pdu microcompartments are thought to be very similar structurally to carboxysomes, the microcompartments involved in carbon fixation in autotrophic cyanobacteria and some chemoautotrophic bacteria. Comparisons of shell proteins of carboxysomes and Pdu microcompartments have shown considerable homology, and it is extremely likely that they assemble to form a similar structure. Studies of carboxysomes have shown that they are regular icosahedral structures and it is thought that Pdu microcompartments also assume roughly this shape, with approximate diameter 120nm. [3]

A regular icosahedron is a polyhedron with twenty equilateral triangular faces, 30 edges, and 12 vertices.[14]