The Sphereactor Team, including attributions and contributions
This is the first iGem team to emerged from Dundee. We are all very excited to be taking part in the competition.
Fordyce Davidson is a Reader of Applied Mathematics. His research interests lie at the interface between the analysis and applications of differential equations, with particular emphasis on applications to biological systems. He continues to work on modelling multi-scale morphology and function of microbes, including the development of fungal mycelia, swimming patterns in Oomycete zoospores and bacterial biofilm formation. He also has an ongoing interest in modelling aspects of the mammalian cell-cycle, with specific focus on the chemo-therapeutic action of small molecule Kinase inhibitors. Dr Davidson is a Fellow of the Institute of Mathematics and its Applications and is a past Vice-President of the British Mycological Society and a BMS Berkeley Award Prize winner. He currently holds an MRC Fellowship focusing on the study of cell differentiation in bacterial biofilms.
Frank is an instructor on the Dundee iGEM 2011 team. Frank was born in the Kingdom of Fife and has a biochemistry degree from the University of Edinburgh. He first came to Dundee in 1992 to undertake a PhD in bacterial genetics and energy metabolism, before leaving Scotland altogether and moving to Norwich, England. Frank returned to Dundee in 2007 as a Professor in the College of Life Sciences. He knows a bit about E. coli physiology, basic molecular biology, and protein chemistry. Hopefully this will come in handy. Frank also has the important job of raising sponsorship for the team and somehow getting everyone to two international jamborees.
I’m a 4th year Biomedical Sciences student with a passion for public health. I’d like to work towards bridging the gap between science and clinical medicine. What initially caught my attention when we were told about the iGEM competition was the prospect of turning ideas into reality from scratch. The opportunity to use my imagination, think outside the box while still building upon my scientific knowledge and skills.
I am a 3rd year Biomedical Science student. A lot of my dedication at university has been directed towards Neurobiology and Pharmacology. However, synthetic biology is a fascinating and relatively new field which is providing me with a unique perspective on science. On my free time I like to rock climb, play golf, read, sing, travel or just hang out with friends.
Lucia Licandro Lado
I was born in Belgium, but have lived most of my life in Spain and Italy. I developed a love for science during high school, and specially for microbiology, because I love the idea of being able to modify microorganisms for our advantage. I also like to read and write short stories.
I am about to start my fourth and final year of Applied Computing at the University of Dundee. I have always had an active interest in technology and love keeping up-to-date with new and current technologies. A lot of my time at University is spent developing software solutions for clients as well as responding to briefs set by lecturers. At the moment I am developing applications and games for smart phones and hope to have them available for download very soon. In my spare time I also like attending festivals and hanging out with friends.
I have just finished my final year of BSc(Hons) in Biomedical Sciences and I am delighted to be graduating with a first class honours. My next step is to further my knowledge through a PhD. My research interests lie in the fields of diabetes and cancer. I look forward to studying the new exciting field of synthetic biology and I believe the practical experience gained through our iGEM project will greatly aid me in pursuit of my PhD. I also like the interdisciplinary element of the project allowing me to take part in a lab work but also the computing and mathematical model building. Outside of the lab I enjoy playing tennis and also reading.
Lionel Dupuy is Research Leader at the James Hutton Institute. He has expertise in computational biology with track record in root system architecture visualisation, image analysis and modelling. His research has made important contributions to the understanding of root system development and interaction with the environment. He has developed various methods for imaging and modelling plant development.
Hi I'm Ciarán and I'm delighted to be an advisor to the Dundee iGEM team 2011! I'm originally from Dublin, Ireland, but came to Scotland in 2002 for my undergraduate degree at the University of Glasgow. I've just gone into the 2nd year of my PhD in Frank Sargent's lab (MMB) and my project is to try and engineer a "superstrain" of E. coli producing lots of biohydrogen! I love my sport and apart from my borderline obsession with football, I like to do a bit of running, tennis, golf and basically any other sport going!
I am about to start my 4th and final year of Mathematical Biology at the University of Dundee. When people ask me what I study, my response nearly always triggers questioning looks, raised eyebrows and comments such as maths and biology?...what an unusual combination!. In actual fact, mathematics has many applications in biology, for example in population dynamics or mathematical modelling of cellular processes. I am particularly interested in the modelling and simulation of tumour growth and its applications in cancer research. Getting involved in the rapidly evolving new field of synthetic biology is going to be a challenging but immensely rewarding experience and I'm very excited to be a part of the interdisciplinary Dundee team for iGEM 2011. When I'm not scribbling down equations, I enjoy climbing, hill-walking, skiing and other outdoorsy activities!
I am an Applied Computing student going into my final year. My interests lie mainly in web application development and learning new languages/skills so coming into this project with minimal biology knowledge has been a fun learning experience. Outside of University, I love to play guitar and my dream is to move to somewhere cold and mountainous like British Columbia, Canada.
I have just finished my final year of a BSc(Hons) in Molecular Genetics and hope to graduate spectacularly this June. I spent most of my two last years of university wreaking havoc in various research labs, where I discovered that my love for budding yeast goes far beyond my simple fondness of beer. Manipulating yeast uses similar techniques to those used for bacteria, so my mad wet-lab skills should come in useful on our quest for iGEM Champions 2011. That being said, I will not tolerate unwashed DNA gel tanks or mistreatment of lab equipment and all culprits will be punished by poking with a pipette tip.
I am a Molecular genetics student coming to terms with the fact I am entering my final year of university. I am interested in anything to do with cells and molecules but also enjoy the microbiology portions of my degree so bring on the bacteria! I love the interdisciplinary element of this project so can’t wait to get started as synthetic biology is a new and exciting area for me. Outside of science I love to cook, play tennis and watch my beloved Dundee United..
Richard is a 3rd year biochemistry student, with interests in how science can be used to approach the global problems we face in a responsible and sustainable manner. I think that synthetic biology is a very interesting expanding field that has potential to address some of these problems, such as climate change and resource shortages. Outside of study I like to spend time with friends, cycling, camping or working on the university allotment.
Thanks to the Division of Cell Signalling & Immunology in the College of Life Sciences, University of Dundee, for giving us lab space and equipment to carry out this project. Thanks also to the Division of Molecular Microbiology for the use of equipment and space. We gratefully acknowledge The Wellcome Trust Rotation Studentship Program for providing molecular biology equipment. We thank all our sponsors for the consumables used in this work. Student stipends over the summer were awarded by The Wellcome Trust (nine studentships), the University of Dundee (one studentship), and the James Hutton Institute (one studentship). Travel funds were provided by the Scottish Universities Life Sciences Alliance (SULSA), the Society for Applied Microbiology (SfAM), the College of Life Sciences, University of Dundee, and the School of Mathematics, University of Dundee.
T-shirt design was the work of Dyce Davidson while cakes and biscuits were baked by random team members.
None of the advisors or instructors are involved in microcompartment research - the project areas were chosen entirely by the team. All cloning and sequencing was carried out by Rachelle, Natasha, Kasia, Lucy, Richard, Brian, Jane and Emelie - overseen, in addition, by Prof Tracy Palmer and Dr Sarah Coulthurst. Our molecular biology "training week" was supervised by Tracy, and we have since never "strayed from the path". Protein production and Western analysis was all done by the team. Confocal and electron microscopy was kindly supervised by Dr. Alan Prescott. Website design was down to Rachel. The iPhone apps were also done by Rachel, while the Android apps were designed by Dave. In addition, Ciaran and Dave conceived the Gene Synthesis tool and Dave made it a reality. The DNA analysis tool was also the work of Dave. Mathematical modelling was figured out by Rachelle, and we thank Lionel for his enthusiasm for iGEM and his modelling workshop afternoon.