Team:ETH Zurich/Achievements
From 2011.igem.org
SmoColi - Achievements
General
- We came up with the idea of a bacterio-quantifier of smoke.
- We worked hard and presented our work during the Regional Jamboree in Amsterdam.
- We received Gold Medal and were invited to advance to the World Championship in Cambridge, USA.
- We documented everything we did in our Wiki Website.
Modeling Achievements
- We made a reaction-diffusion model for the toxic molecule gradient formation in a channel and got a feeling about the feasibility of our ideas and channel dimensions.
- We approximated the gradient analytically and checked that it almost coincides with the numerically obtained one.
- We made a single cell model describing our circuit and verified its operation.
- We performed a robustness analysis of our system to see how the band behaves upon parameter variations and concluded that it is robust and monostable.
- We performed stochastic analysis to see how the GFP band reacts upon noise and concluded one more time about its robustness
- We integrated the single cell model and the reaction-diffusion model in a combined 3D spatiotemporal reaction-diffusion model, simulated for various channel dimensions to get a feeling how the GFP band will move and how the alarm is activated
- We extracted some information about the channel dimensions from the model and used this information in the actual channel design.
Biology
Microfluidics
- We sistematically came up with the current channel design through a process of developing and refining chain of ideas for different designs.
- We participated in the PDMS channel construction.
- We tested the microfluidics channel and assured ourselves that our cells can survive and we can form a gradient inside.
Human Practices
- We presented Synthetic Biology and iGEM to our fellow students in the CBB get together afternoon.
- We presented iGEM and our project to the general public on the BSSE Open House Day through a poster and a slide show
- We also made a survey with critical questions related to Synthetic Biology and iGEM, asked people to fill it out and analyzed the results.
- ETH GLOBE ?
Miscelaneous
- Laura managed to move the Dropbox folder to another location, thus making it look empty for the others.
- Sabine ... what exactly she did?
- We had fun!
Section A
Test
Subsection
More testing