SmoColi - Achievements

Modeling Achievements

• We made a reaction-diffusion model for the toxic molecule gradient formation in a channel and got a feeling about the feasibility of our ideas and channel dimensions.
• We approximated the gradient analytically and checked that it almost coincides with the numerically obtained one.
• We made a single cell model describing our circuit and verified its operation.
• We performed a robustness analysis of our system to see how the band behaves upon parameter variations and concluded that it is robust and monostable.
• We performed stochastic analysis to see how the GFP band reacts upon noise and concluded one more time about its robustness
• We integrated the single cell model and the reaction-diffusion model in a combined #D spatiotemporal reaction-diffusion model, simulated for various channel dimensions to get a feeling how the GFP band will move and how the alarm is activated
• We extracted some information about the channel dimensions and used this in the actual channel design

Biology achievements

Section A

Test

Subsection

More testing