Team:UCL London/Bibliography

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Bibliography

Supercoilometer

  1. Straney, R., R. Krah, and R. Menzel, Mutations in the -10 Tataat Sequence of the Gyra Promoter Affect Both Promoter Strength and Sensitivity to DNA Supercoiling. Journal of Bacteriology, 1994. 176(19): p. 5999-6006.
  2. Pemberton, I.K., et al., The G+C-rich discriminator region of the tyrT promoter antagonises the formation of stable preinitiation complexes. Journal of Molecular Biology, 2000. 299(4): p. 859-864.
  3. Lamond, A.I., Supercoiling response of a bacterial tRNA gene. Embo Journal, 1985. 4(2): p. 501-7.
  4. Bowater, R.P., D.R. Chen, and D.M.J. Lilley, Modulation of Tyrt Promoter Activity by Template Supercoiling in-Vivo. Embo Journal, 1994. 13(23): p. 5647-5655.
  5. El Hanafi, D. and L. Bossi, Activation and silencing of leu-500 promoter by transcription-induced DNA supercoiling in the Salmonella chromosome. Molecular Microbiology, 2000. 37(3): p. 583-594.
  6. Bossi, L., et al., The supercoiling sensitivity of a bacterial tRNA promoter parallels its responsiveness to stringent control. Embo Journal, 1998. 17(8): p. 2359-2367.

Manufacturing

  1. 1. Williams, J.A. and Carnes, A. E., 2007. Plasmid DNA manufacturing technology. Recent Patents on Biotechnology, Vol.1, No.2.
  2. 2. Lin-Chao, S, Bremer, H., 1986. Effect of the bacterial growth rate on replication control of plasmid pBR322 in Escherichia coli. Molecular and General Genetics. 203(1):143-9
  3. 3. O'Kennedy, R.D., et al., 2000. Effects of growth medium selection on plasmid DNA production and initial processing steps. Journal of Biotechnology. 76(2-3):175-83.
  4. 4. Levy, M. S., et al., 1999. Effect of shear on plasmid DNA solution. Bioprocess Engineering, 20, 7-13.
  5. 5. U.S. Food and Drug Administration, 2007. Guidance for industry: consideration for plasmid DNA vaccines for infectious disease indications.
  6. 6. Catanese Jr, D.J. et al, 2011. Supercoiled minivector DNA resists shear forces associated with gene therapy delivery. Gene Therapy, 1-7
  7. 7. Carnes, A.E., 2005. Fermentation Design for the manufacture of therapeutic plasmid DNA. Bioprocess Technical.
  8. 8. Hoare, M., et al., 2005. Bioprocess engineering issues that would be faced in producing a DNA vaccine at up to 100m3 fermentation scale for an influenza pandemic. Biotechnology Progress, 2005, 21, 1577-1592.
  9. 9. Oram, M., et al., 2003. A biochemical analysis of the interaction of DNA gyrase with the bacteriophage Mu, pSC101 and pBR322 strong gyrase sites: the role of DNA sequence in modulating gyrase supercoiling and biological activity. Molecular Microbiology, 50 (1): 333-347.
  10. Ferreira, G.N.M, et al., 2000. Downstream Processing of plasmid DNA for gene therapy and DNA vaccine applications. Trends in biotechnology, 18.
  11. 11. Dorman CJ. et al., 1991. DNA supercoiling and the anaerobic and growth phase regulation of tonB gene expression. Infection and Immunity, 59(3): 745–749.
  12. 12. Hsieh, L.S., et al., 1991. Bacterial dna supercoiling and [ATP]/[ADP] changes associated with a transition to anaerobic growth. Journal of Molecular Biology, 219(3):443-50.
  13. 13. Hopkins D.J., et al., 1987. Effects of dissolved oxygen shock on the stability of recombinant ecoli containing plasmid pKN401. Biotechnology and Bioengineering, 29 (1): 85-91.
  14. 14. Durland, R.H., and Easman, E.M., 1998. Manufacturing and quality control of plasmid based gene expression of pBR322-derived plasmids intended for human gene therapy by employing a temperature-controllable point mutation. Advanced Drug Delivery Review, 2;30(1-3):33-48.
  15. 15. Cupillard, L., et al., 2005. Impact of plasmid supercoiling on the efficacy of a rabies DNA vaccine to protect cats. Vaccine, 23: 1910–1916.
  16. 16. Carnes, A.E., et al., 2009. Plasmid DNA Production Combining Antibiotic-Free Selection, Inducible High Yield Fermentation, and Novel Autolytic Purification. Biotechnology and Engineering, 104 (3): 505-515.

Medicine

  1. http://www.tsim.org.tw/article/A95/abstract/10-afternoon/Rm102/H5N1-3.pdf
  2. WHO, Avian Influenza, [Online] Available at: [Accessed on 16 September 2011)
  3. TED, Seth Berkley: HIV and flu -- the vaccine strategy, [Online] Available at: [Accessed on 14 September 2011)
  4. http://www.medscape.com/viewarticle/487616
  5. Recombinant/ purified protein vaccines, [Online] Available at: [Accessed on 17 September 2011)
  6. Discover Magazine: Vaccine Production Is Horribly Outdated. Here Are 3 Ways to Fix It. [Online] Available at: [Accessed on 17 September 2011)
  7. www.pitt.edu/~super7/32011-33001/32731.ppt
  8. NAE Website - Cell-Culture-Based Vaccine Production: Technological Options, [Online] Available at: [Accessed on 16 September 2011)
  9. David B. Weiner and Ronald C. Kennedy, 1999. Genetic Vaccines. Scientific American, July Issue, pp. 50-57. Cui, Z., 2005. DNA vaccine. Advances in Genetics, Volume 54, pp. 257-289. DNA vaccination: Immune response raised by DNA vaccines [online] Available at: [Accessed on 7 September 2011] David B. Weiner and Ronald C. Kennedy, 1999. How DNA Vaccines Work. [diagram] Same journal.
  10. Wikipedia, Gene gun, [online] Available at: [Accessed on 8 September 2011)
  11. Inovio, Technology: Electroporation-Based DNA Delivery, [online] Available at: [Accessed on 8 September 2011)
  12. Pilling et al., 2002. The Assessment of Local Tolerance, Acute Toxicity, and DNA Biodistribution Following Particle-Mediated Delivery of a DNA Vaccine to Minipigs. Toxicologic Pathology, 30(3), pp 298-305.
  13. Sheets et al., 2006. Biodistribution of DNA Plasmid Vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile Virus Is Similar, without Integration, despite Differing Plasmid Backbones or Gene Inserts. Toxicological Sciences, 91(2), pp 610-619.
  14. Sheets et al., 2006. Toxicological Safety Evaluation of DNA Plasmid Vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile Virus Is Similar Despite Differing Plasmid Backbones or Gene-Inserts. Toxicological Sciences, 91(2), pp 620-630
  15. http://www.academicjournals.org/AJB/PDF/pdf2011/7Sep/Roy%20et%20al.pdf
  16. NAE Website - Cell-Culture-Based Vaccine Production: Technological Options, [Online] Available at: [Accessed on 7 September 2011)
  17. Strategies for production of viral vaccines, [Online] Available at: [Accessed on 14 September 2011)
  18. Strategies for production of viral vaccines, [Online] Available at: [Accessed on 14 September 2011)
  19. Strategies for production of viral vaccines, [Online] Available at: [Accessed on 14 September 2011)
  20. U.S. Department of Health and Human Services, CBER and FDA Guidance document. Guidance for Industry: Considerations for Plasmid DNA Vaccines for Infectious Disease Indications (11/07)
  21. Urthaler et al., 2005. Improvement of transfection efficiency by using supercoiled plasmid DNA purified with arginine affinity chromatography. J Gene Med, 11(1): 79-88.
  22. Cupillard et al., 2005. Impact of plasmid supercoiling on the efficacy of a rabies DNA vaccine to protect cats. Vaccine, 23: 1910-1916.
  23. Jensen et al., 1999. Extensive regulation compromises the extent to which DNA gyrase controls supercoiling and growth rate of Escherichia coli. Eur. I. Biochem., 266: 865-877.
  24. Trigueros S and Roca J, 2002. Failure to relax negative supercoiling of DNA is a primary cause of mitotic hyper-recombination in topoisomerase-deficient yeast cells. J Biol Chem., 277(40):37207-11.

Safety

  1. Cupillard, L. et al., 2005. Impact of plasmid supercoiling on the efficacy of a rabies DNA vaccines to protect cats. Vaccine 23: 1910-1916.
  2. Reece, R.J. and Maxwell, A., 1991. DNA Gyrase: Structure and Function. Critical Reviews in Biochemistry and Molecular Biology. 26 (3/4):335-375.
  3. Safety Handbook, 2010/2011. Department of Biochemical Engineering,UCL.
  4. Institute of Child Health Flow Cytometry Core Facility, UCL Biosafety: Important health and safety documents, [online]
    Available from: http://www.ucl.ac.uk/ich/services/lab-services/FCCF/biosafety (Accessed on 25 August 2011)

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