Team:USTC-Software

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Team:USTC-Software - 2011.igem.org

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What is iGEM?

The International Genetically Engineered Machine competition (iGEM) is the premiere undergraduate Synthetic Biology competition. Student teams are given a kit of biological parts at the beginning of the summer from the Registry of Standard Biological Parts. Working at their own schools over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells. This project design and competition format is an exceptionally motivating and effective teaching method.

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What is Project Lachesis?

The project Lachesis aims at providing and integrated, easy-using and extensible CAD environment for the general purpose of Synthetic Biology, it adopts an plug-in based structure.We provide three categories of plug-ins:Document parsers that handles various types of files, such as SBML andMoDeL. Models that each represents a specific kind of synthetic biological model. Views that present graphical user interface for users to work with biological models.

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Where are we from?

The University of Science and Technology of China (USTC) is under the jurisdiction of the Chinese Academy of Sciences (CAS). As a key university of the nation, it is noted for its advanced science and high technology programs, unique management studies and well-tailored disciplines in the humanities. On May 11, the Nature Publishing Group released Nature Publishing Index 2010 China, remarking "a dramatic rise in the quality of research being published by China". University of Science and Technology of China is ranked 3rd of TOP 10 Institutions in Index 2010 China.

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Lachesis

Team

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Our team is formed of a group of diligent students coming from various departments of USTC. In the School of Life Sciences, we devoted out perspiration to this project for nearly a year.

MoDeL

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Biological reaction networks, even small ones, contain lot of species and reaction and, thus, are hard to build by hand. Our rule-based modeling approch aims at freeing human from such labor.

Human practice

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We conducted a survey, during National Science Week, to discover USTC students' opinion on Synthetic Biology.

Project

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Our project of this year is Lachesis, which provide functions including:

1、Automatically generating biological reaction network from assembly structure constructed by user.

2、Fitting a biological reaction network's parameters to experiment data or hand drawn curves.

3、Evaluating the sensitivity and robustness of a biological reaction network.

4、Making biological reaction network easy to work with by the methods of visualization.

   

Sponsers

Initiative Foundation, USTC

Teaching Affair Office, USTC

School of Life Sciences, USTC

Graduate School, USTC

School of Chemistry and Materials Science, USTC


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