Team:UST-Beijing/Team

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Revision as of 06:02, 5 August 2011

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Home	Team	Official Team Profile	Project	Parts Submitted to the Registry	Modeling	Notebook	Safety	Attributions

Who we are

Advisors:

Advisor 1: ChingSong*Advisor 2: Our favorite ChingSong
Grad Student 1: Our leader Hanzhong Ke

Undergrads:

Student 1: Danyang Wang
Student 2: Lujun Zhou
Student 3: Fang Li, Is going to save the world
Student 4: Wenjing Zhang Loves iGEM
Student 5: A normal student... or(r) am I?
Student 6: Table football fan
Student 7:

UST-Beijing Team member 1.png Team member 1	UST-Beijing Team member 2.png Team member 2	UST-Beijing Team member 3.png Team member 3	UST-Beijing Team member 4.png Team member 4
UST-Beijing Team member 5.png Team member 5	UST-Beijing Team member 6.png Team member 6	UST-Beijing Team member 7.png Team member 7

What we did

We using lacI DNA-binding domain and LXRbeta ligand-binding domain, we made an artificial bile acid receptor which can regulate expression of target gene within a natural lacI operon. As proof of principle, we demonstrate that regulation of bacteria gene expression by host eukaryocyte metabolites is achievable using chimeric nuclear receptors. Through directed molecular evolution, a harmonious signal network regulating metabolism of both prokaryocytes and their host eukaryocytes in the digestive tract is feasible.

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 == '''What we did''' ==
-(Provide proper attribution for all work)
+We using lacI DNA-binding domain and LXRbeta ligand-binding domain, we made an artificial bile acid receptor which can regulate expression of target gene within a natural lacI operon. As proof of principle, we demonstrate that regulation of bacteria gene expression by host eukaryocyte metabolites is achievable using chimeric nuclear receptors. Through directed molecular evolution, a harmonious signal network regulating metabolism of both prokaryocytes and their host eukaryocytes in the digestive tract is feasible.
 == '''Where we're from''' ==