Team:Amsterdam/12 May 2011

From 2011.igem.org

Revision as of 10:26, 21 September 2011 by B.Stringer (Talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

April
MTWTFSS
        1 2 3
4 5 6 7 8 9 10
11 12 13 14 15 16 17
18 19 20 21 22 23 24
25 26 27 28 29 30
May
MTWTFSS
            1
2 3 4 5 6 7 8
9 10 11 12 13 14 15
16 17 18 19 20 21 22
23 24 25 26 27 28 29
30 31
June
MTWTFSS
    1 2 3 4 5
6 7 8 9 10 11 12
13 14 15 16 17 18 19
20 21 22 23 24 25 26
27 28 29 30
July
MTWTFSS
        1 2 3
4 5 6 7 8 9 10
11 12 13 14 15 16 17
18 19 20 21 22 23 24
25 26 27 28 29 30 31
August
MTWTFSS
1 2 3 4 5 6 7
8 9 10 11 12 13 14
15 16 17 18 19 20 21
22 23 24 25 26 27 28
29 30 31
September
MTWTFSS
      1 2 3 4
5 6 7 8 9 10 11
12 13 14 15 16 17 18
19 20 21 22 23 24 25
26 27 28 29 30
October
MTWTFSS
          1 2
3 4 5 6 7 8 9
10 11 12 13 14 15 16
17 18 19 20 21 22 23
24 25 26 27 28 29 30
31


12-05-11 | UvA Meeting for topics discussion

Neglected disease

Kala-azar

  • Protein is unstable if it is secreted
  • This is difficult to use in E. coli
  • A heat test can be used, but will not yield any biobricks
  • Peanut agluttin binds to LPG
    • This LPG can be found in multiple organisms
      • This will lead to false positives
  • Are there antibodies against the promastigotes/amastigotes?
    • This will be checked

Hookworm

  • Detectable in human blood
  • GP63 protein is expressed in multiple diseases
  • This can't be the target protein

Buruli ulcer

  • Is mycolactone specific for this disease?
  • When ARP is present, mycolactone is inactive
  • Use the receptor that M. ulcerans binds to and place it onto an E. coli
  • Can we order mycolactone?

Target the host not the disease!

  • We will look into this
  • Attract the parasite with a pheromone

Ethylene producing E.coli

  • Evolution takes to long for iGEM
    • It doesn't produce biobricks
  • Some literature about the topic will be sent to us